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Recent Publications

Kim, J., Chen, C-P. and Rice, K.G. “The Proteasome Metabolizes Peptide-Mediated Nonviral Gene Delivery Systems” Gene Therapy (2005) 12, 1581 – 1590.Copper-Mediated Displacements of Allylic THP Ethers on a Bisphosphonate Template, Shull, L. W.; Wiemer, D. F. J. Organomet. Chem . 2005 , 690, 2521–2530.

Synthesis of Nonracemic 3-Deoxyschweinfurthin B. Neighbors, J. D.; Beutler, J. A.; Wiemer, D. F. J. Org. Chem. 2005, 70, 925–931.

Total synthesis of pawhuskin C: A dianion directed ortho metallation approach. Neighbors, J. D.; Salnikova, M. S.; Wiemer, D. F. TetrahedronLetters 2005, 46, 1321–1324.

Application of benzyl protecting groups in the synthesis of prenylated aromatic compounds. Odejinmi, S. I.; Wiemer, D. F. TetrahedronLetters 2005, 46, 3871 –3874.

Synthesis of Arieianal, a Prenylated Benzoic Acid from Piper arieianum. Odejinmi, S. I.; Wiemer, D. F. J. Natural Products 2005, 68, 1375 – 1379.

Synthesis of Aromatic Phosphates via Cycloaddition of Phosphate Dienes. Kim, M. K.; Wiemer, D. F. TetrahedronLetters 2005 , 46, 7583 – 7587.

Synthesis of Farnesol Isomers via a Modified Wittig Procedure. Yu, J. S.; Kleckley, T. S.; Wiemer, D. F. Org. Lett. 2005 , 7, 4803 – 4806.

Synthesis and Structure Activity Studies of Schweinfurthin B Analogs: Evidence for the Importance of a D-Ring Hydrogen Bond Donor in Expression of Differential Cytoxicity. Neighbors, J. D.; Salnikova, M. S.; Beutler, J. A.; Wiemer, D. F. Bioorg Med. Chem.2005, in press.

The Schweinfurthins: Issues in Development of a Plant-Derived Anticancer Lead. Beutler, J. A.; Jato, J.; Cragg, G.; Wiemer, D. F.; Neighbors, J. D.; Salnikova, M. S.; Hollingshead, M.; Scudiero, D. A.; McCloud, T. G. In: Medicinal and Aromatic Plants, edited by R. J. Bogers, Springer, 2005, in press.

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