CBB Milestones

2011

Completed 2 successful vaccine campaigns.

Successfully scaled up Picha fermentaton to 500 Liters.

Completed Tech transfer of Pyruvate production via biocatalysis.

2008-2010
Completed over 50 successful cGMP campaigns. IND filing by one of our clients.
2007
Grand Opening of cGMP Fermentaion Facility. Validation of critical equipment and performance of engineering runs.
2006
Start construction of cGMP fermentation facility.
2004-2005

NSF Engineering Research Center for Environmentally Beneficial Catalysis funded.

CBB Director search initiated in 2004.

State of Iowa awarded $3 million for construction of cGMP facility in 2004.

Purchase of former Apovia laboratory for purification component of cGMP facility in 2005.

New CBB Director Mani Subramania joins in October 2005.

1999 -2000

3rd NIH Training Grant – led by Professor Daniel Quinn.

E. I. DuPont de Nemours and Co. donates gift of 14 patents on glycolate oxidase (GO) technology to the UI through the CBB.

UI DuPont Mini-symposium on GO technology held in June 1999.

Grants to develop GO technology awarded in October 1999.

1996

Final equipping of the CBB lab. Twenty-two fermentors, downstream and analytical equipment.

Establishment of Research and Process Development laboratory (RPD).

Recruitment, training and building an experienced laboratory staff.

First grants/contracts for fermentation bioprocessing in CBB Laboratory.

NSF Training Grant - Gene Expression in Bioremediation led by E.P. Greenberg and Gene Parkin.

1995-2000

2nd NIH Biotechnology Training Grant - led by David T. Gibson.

1993-1995

Planning and architectural development of the CBB Laboratory at Oakdale - led by a multi-departmental committee.

Construction, initial equipping and staffing of the CBB laboratory.

UI Core Fermentation Facility moved to CBB lab.

1991

1st annual CBB Conference held in Iowa City.

1990

CBB receives Board of Regents recognition as “The Center for Biocatalysis and Bioprocessing” in the State of Iowa.

Won 1st NIH Training Grant in Biotechnology in 1990 marked scientific peer recognition of the strength of the CBB led by Prof. David. T. Gibson.

CBB awards first predoctoral fellowships.

1st funding from state of Iowa to formally establish the CBB, and support establishment of a governing structure, standing committees and staff.

Industrial affiliates program established.

2nd Industry-University "Mini-symposium" held with scientists from Eli Lilly.

1989

First Industry-University biocatalysis “Mini-symposium” with Eastman Kodak.

Eastman Kodak donates $37,000 to the Biocatalysis Research group for the support of three predoctoral fellows.

1987

Professor David T. Gibson accepts the 1st Endowed Chair in Biocatalysis in the USA after a worldwide search by a multi-departmental committee.

1984

The 1st UI Fermentation Facility through an NSF grant led by Professor Lacy Daniels with participation of Biocatalysis faculty.

1983

Biocatalysis Research Group founded - 15 faculty members from five departments.

The Biocatalysis Seminar program began in 1983.

More than 250 top scientists from throughout the world invited since then.

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