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CBB Milestones

1983

Biocatalysis Research Group founded - 15 faculty members from five departments.

The Biocatalysis Seminar program began in 1983.
More than 250 top scientists from throughout the world invited since then.

1984

The 1st UI Fermentation Facility through an NSF grant led by Professor Lacy Daniels with participation of Biocatalysis faculty.

1987

Professor David T. Gibson accepts the 1st Endowed Chair in Biocatalysis in the USA after a worldwide search by a multi-departmental committee.

1989

First Industry-University biocatalysis “Mini-symposium” with Eastman Kodak.

Eastman Kodak donates $37,000 to the Biocatalysis Research group for the support of three predoctoral fellows.

1990

CBB receives Board of Regents recognition as “the Center for Biocatalysis and Bioprocessing” in the State of Iowa.

Won 1st NIH Training Grant in Biotechnology in 1990 marked scientific peer recognition of the strength of the CBB led by Prof. David. T. Gibson.

CBB awards first predoctoral fellowships.

1st funding from state of Iowa to formally establish the CBB, and support establishment of a governing structure, standing committees and staff.

Industrial affiliates program established.

2nd Industry-University "Mini-symposium" held with scientists from Eli Lilly.

1991

1st annual CBB Conference held in Iowa City.

1993-1995

Planning and architectural development of the CBB Laboratory at Oakdale - led by a multi-departmental committee.

Construction, initial equipping and staffing of the CBB laboratory.

UI Core Fermentation Facility moved to CBB lab.

1995-2000

2nd NIH Biotechnology Training Grant - led by David T. Gibson.

1996

Final equipping of the CBB lab. Twenty-two fermentors, downstream and analytical equipment.

Establishment of Good Laboratory Practice (GLP) mode of operation.

Recruitment, training and building an experienced laboratory staff.

First grants/contracts for fermentation bioprocessing in CBB Laboratory.

NSF Training Grant - Gene Expression in Bioremediation led by E.P. Greenberg and Gene Parkin.

1999 -2000

3rd NIH Training Grant – led by Professor Daniel Quinn.

E. I. DuPont de Nemours and Co. donates gift of 14 patents on glycolate oxidase (GO) technology to the UI through the CBB.

UI DuPont Mini-symposium on GO technology held in June 1999.

Grants to develop GO technology awarded in October 1999.

2004-2005

NSF Engineering Research Center for Environmentally Beneficial Catalysis funded.

CBB Director search initiated in 2004.

State of Iowa awarded $3 million for construction of cGMP facility in 2004.

Purchase of former Apovia laboratory for purification component of cGMP facility in 2005.

New CBB Director Mani Subramania joins in October 2005.

2006
Start construction of cGMP fermentation facility.
2007
Completion of cGMP fermentation facility with validation of facility and engineering runs.
2008
Four successful cGMP campaigns and an IND filing by a client.

 

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