Abstracts

21st Annual CBB Conference "Current Topics in Industrial Biotechnology"

October 15-16, 2012
University of Iowa
Iowa Memorial Union, Iowa City, IA

Please check back later for 2012 conference poster information

 

20th Annual CBB Conference Poster Abstracts

  1. EFFECT OF A MUTANT WITH ALTERED DYNAMICS ON HYDRIDE TRANSFERS CATALYZED BY THYMIDYLATE SYNTHASE
    Thelma Abeysinghe, Zhen Wang and Amnon Kohen*
    Department of Chemistry, College of Liberal Arts and Sciences, The University of Iowa, Iowa City, IA 52242
  2. ROLE OF HOMOLOG CuZnSOD IN VIRAL PROPAGATION
    Bhakti Bapat and David Murhammer*
    Department of Chemical and Biochemical Engineering, College of Engineering, The University of Iowa, Iowa City, IA 52242
  3. MATERIALS-BASED APPROACH TO IMPLANT INFECTION MITIGATION
    Ann Baumhoer and Eric Nuxoll*
    Department of Chemical and Biochemical Engineering, College of Engineering, The University of Iowa, Iowa City, IA 52242
  4. SYNTHESIS OF N-ARYLACYL O-SULFONATED AMINOGLYCOSIDES THAT BIND HEPARAN SULFATE BINDING PROTEINS
    Ioana Craciun, Amanda M. Fenner and Robert J. Kerns*
    Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  5. ENHANCING GENE DELIVERY THROUGH NUCLEAR TARGETED PLA2
    Samuel T. Crowley, Nick Baumhover and Kevin G. Rice*
    Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  6. MULTICELLULAR DEVELOPMENT IN MYXOCOCCUS XANTHUS REQUIRES THE PUTATIVE FATTY ACID DESATURASE DES7
    Cynthia Darnell and John Kirby*
    Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA 52242
  7. BIOCATAYTIC PRODUCTION OF XYLITOL FROM CORN STOVER HEMICELLULOSE HYDROLYSATE AND PURIFICATION OF THE PRODUCT BY SMB CHROMATOGRAPHY
    Shuvendu Das1, Michael Louie1, Naveen Sudharsan2, Anil Oroskar2 and Venkiteswaran Subramanian1*
    1Center for Biocatalysis and Bioprocessing, The University of Iowa Research Park, Coralville, IA 52241
    2Orochem Technologies Inc.1, Lombard, IL 60148
  8. EVALUATION OF qPCR PRIMERS TO DETECT METHANOTROPHS IN CONTAMINATED GROUNDWATER
    Meredith L Dobson, and Timothy E Mattes*
    Department of Civil and Environmental Engineering, College of Engineering, The University of Iowa, Iowa City, IA 52242
  9. MICROGLIA AND A DOPAMINE-DERIVED NEUROTOXIN, 3,4-DIHYDROXYPHENYLACETALDEHYDE: TOXICITY, METABOLISM, ACTIVATION, AND IMPLICATIONS FOR PARKINSON’S DISEASE
    Laurie L. Eckert, Virginia R. Florang, Jonathan A. Doorn*
    Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  10. INVESTIGATING THE IMPACT OF METHYL – HYDROGEN EXCHANGE ON SUPRAMOLECULAR SOLID-STATE SELF-ASSEMBLY AND REACTIVITY: DIRECTED STEREOSPECIFIC PHOTOCYCLOADDITIONS OF TRISUBSTITUTED OLEFINIC ESTERS
    Elizabeth Elacqua, Joseph C. Sumrak, Paul T. Jurgens, Bradley Loren, Poonam Kaushik, Ryan Groeneman, Dejan-Krešimir Bucar and Leonard R. MacGillivray*
    Department of Chemistry, College of Liberal Arts and Sciences, The University of Iowa, Iowa City, IA 52242
  11. THE SOLID PHASE SYNTHESIS OF REDUCIBLE POLYPEPTIDES
    Mark D. Ericson and Kevin Rice*
    Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  12. ENGINEERING OF CHLORELLA VULGARIS FOR BIOCATALYSIS TO GENERATE HIGH VALUE PRODUCTS
    Todor Genkov, Michael Louie and Mani Subramanian*
    Center for Biocatalysis and Bioprocessing, The University of Iowa Research Park, Coralville, IA 52241
  13. COMPARISON OF PURIFICATION OF RECOMBINANT N-DEMTHYLASE B (NdmB) USING SIMULATED MOVING BED AFFINITY CHROMATOGRAPHY (SMB) AND FPLC
    Juan Antonio Moreno-Cid Mora1, Jingying Xu2, Sridhar R. Gopishetty2 and Mani Subramanian2,3*
    1Dpto. De Sanidad Animal, Instituto de Investigaciones en Recursos Cinegéticos, IREC, Ronda de Toledo, Spain
    2Center for Biocatalysis and Bioprocessing, The University of Iowa Research Park, Coralville, IA 52241
    3Department of Chemical and Biochemical Engineering, College of Engineering, The University of Iowa, Iowa City, IA 52242
  14. SYNTHESIS OF PICOLYL AZIDE ANALOGUES OF NICOTINAMIDE AS POTENTIAL TWO-DIMENSIONAL INFRARED PROBES OF NAD(P)-DEPENDENT ENZYME DYNAMICS
    Qi Guo, Philip Pagano, Christopher Cheatum* and Amnon Kohen*
    Department of Chemistry, College of Liberal Arts and Sciences, The University of Iowa, Iowa City, IA 52242
  15. IDENTIFYING OPTIMAL CONDITIONS FOR DETECTING VARING CONCENTRATIONS OF ATRAZINE USING RAMAN SPECTROSCOPY
    Victoria A. Henry, Julie L. Jessop* and Tonya L.Peeples*
    Department of Chemical and Biochemical Engineering, College of Engineering, The University of Iowa, Iowa City, IA 52242
  16. 4-HNE AND CCG-4986 COVALENTLY MODIFY RGS4 AT CYS148 TO ALLOSTERICALLY DISRUPT G PROTEIN BINDING
    Colin A. Higgins and David L. Roman*
    Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  17. BUILDING CHEMICAL LIBRARIES OF SPATIALLY COMPLEX TRICYCLIC MOLECULES USING A CASCADE REACTION
    Angela Horst, Verónica M. Rivas and Horacio F. Olivo*
    Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  18. DEVELOPMENT OF MOLECULAR BIOLOGY TOOL FOR MONITORING BIOREMEDIATION OF VINYL CHLORIDE IN GROUNDWATER
    Yang Oh Jin and Timothy E. Mattes*
    Civil and Environmental Engineering, College of Engineering, The University of Iowa, Iowa City, IA 52241
  19. MITOCHONDRIAL TARGETED TRIPHENYLPHOSPHONIUM DERIVATIVES FOR TREATMENT OF METASTATIC MELANOMA
    Kyle C. Kloepping, Douglas R. Spitz and Michael K. Schultz*
    Department of Radiation Oncology (Free Radical and Radiation Biology Program), Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA 52242
  20. VC DEGRADATION BY METHANE-OXIDIZING AND ETHENE-OXIDIZING BACTERIA IN THE PRESENCE OF METHANE AND ETHENE MIXTURES
    Meng Chen Lee and Timothy E. Mattes*
    Department of Civil and Environmental Engineering, College of Engineering, The University of Iowa, Iowa City, IA 52242
  21. BACTERIAL COMMUNITY STRUCTURES AND POLYCHLORINATED BIPHENYL BIODEGRADATION POTENTIAL IN SEDIMENTS FROM INDIANA HARBOR SHIPPING CANAL
    Yi Liang, Joshua A. Livermore, Andres Martinez, Keri C. Hornbuckle and Timothy E. Mattes*
    Department of Civil and Environmental Engineering, College of Engineering, The University of Iowa, Iowa City, IA 52242
  22. KINETIC EVALUATION OF DUAL BINDING HUMAN ACETYLCHOLINESTERASE INHIBITORS
    Alexander M. Lodge, Manza B. Atkinson, Elizabeth Elacqua, Daniel M. Quinn* and Leonard R. MacGillivray*
    Department of Chemistry, College of Liberal Arts and Sciences, The University of Iowa, Iowa City, IA 52242
  23. HIGH-THROUGHPUT SCREENING AND CHARACTERIZATION OF SMALL MOLECULE INHIBITORS OF THE Gα:RGS17 PROTEIN: PROTEIN INTERACTION FOR TREATMENT OF LUNG AND PROSTATE CANCERS
    Duncan I. Mackie and David L. Roman*
    Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  24. CHEMICAL TRAPPING OF AN INTERMEDIATE IN THE REACTION CATALYZED BY FLAVIN-DEPENDENT THYMIDYLATE SYNTHASE
    Tatiana Mishanina, Eric M. Koehn, John A. Conrad, Bruce A. Palfey, Scott A. Lesley and Amnon Kohen*
    Department of Chemistry, College of Liberal Arts and Sciences, The University of Iowa, Iowa City, IA 52242
  25. NEW PATHWAY FOR CAFFEINE DEGRADATION IN PSEUDOMONAS sp. CBB1: NOVEL ENZYMES, GENES, AND METABOLITES
    Sujit K. Mohanty, Chi Li Yu and Mani Subramanian*
    Department of Chemical & Biochemical Engineering, College of Engineering, The University of Iowa, Iowa City, IA 52242 and Center for Biocatalysis & Bioprocessing, The University of Iowa Research Park, Coralville, IA 52241
  26. MODIFICATION AND FUNCTIONAL INHIBITION OF REGULATOR OF G-PROTEIN SIGNALING 4 BY 4-HYDROXY-2-NONENAL
    C. Aaron Monroy and David L. Roman*
    Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  27. BEAUVARIA BASSIANA OXIDATIVE PERFORMANCE
    Felipe Nicolau-Manterola1, Richard Gonzalez1, Tonya L. Peeples1* and Horacio F. Olivo2*
    1Department of Chemical and Biochemical Engineering, College of Engineering, The University of Iowa, Iowa City, IA 52242
    2Division of Medicinal and Natural Products Chemistry College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  28. PROBING THE PROPERTIES OF NANOPORES IN POROUS SILICA CHROMATOGRAPHY RESINS VIA SINGLE MOLECULE SPECTROSCOPY
    Cicily Ronhovde and M. Lei Geng*
    Department of Chemistry, College of Liberal Arts and Sciences, The University of Iowa, Iowa City, IA 52242
  29. ROLE OF THE DNA-BINDING PROTEIN IsaB IN STAPHYLOCOCCUS AUREUS BIOFILMS
    Carolyn B. Rosenthal and Alexander R. Horswill*
    Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, The University of Iowa, Iowa City, IA 52242
  30. USING KINETIC ISOTOPE EFFECTS TO ASSESS DYNAMIC MOTIONS OF THE SUBSTRATES IN ENZYMATIC H-TRANSFERS
    Daniel Roston, Christopher M. Cheatum and Amnon Kohen*
    Department of Chemistry, College of Liberal Arts and Sciences, The University of Iowa, Iowa City, IA 52242
  31. ORGANIC NANOCRYSTALS OF SUPRAMOLECULAR MATERIALS
    John R. G. Sander1, Dejan-Krešimir Bucar1, Rodger F. Henry2, Jonas Baltrusaitis1,3, Geoff G. Z. Zhang4* and Leonard R. MacGillivray1*
    1Department of Chemistry, College of Liberal Arts and Sciences, The University of Iowa, Iowa City, IA 52242
    2Structural Chemistry, Global Pharmaceutical R&D, Abbott Laboratories, Abbott Park, IL 60064
    3Central Microscopy Research Facility, The University of Iowa, Iowa City, IA 52242
    4Materials Science, Global Pharmaceutical R&D, Abbott Laboratories, Abbott Park, IL 60064
  32. DIFFERENTIAL BINDING OF DNA WITH FLUOROQUINOLONES AFFECTS THE ABILITY OF THE FLUOROQUINOLONE TO KILL MICROORGANISMS
    Heidi A. Schwanz and Robert J. Kerns.*
    Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  33. HIGHLY EFFICIENT SYNTHESIS OF NOVEL OSW-1 ANALOGS
    Aashay K. Shah and Zhendong Jin*
    Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  34. NANOSTRUCTURED PHOTO CROSS-LINKED BIOPOLYMERS IN WOUND-HEALING AND DRUG DELIVERY APPLICATIONS
    Kristan L. Sorenson1, C. Allan Guymon1* and Aliasger K. Salem2*
    1Department of Chemical and Biochemical Engineering, College of Engineering, The University of Iowa, Iowa City, IA 52242
    2Department of Pharmaceutics, College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  35. SUPRAMOLECULAR CATALYSIS IN THE ORGANIC SOLID STATE
    Jelena Stojakovic and Leonard R. MacGillivray*
    Department of Chemistry, College of Liberal Arts and Sciences, The University of Iowa, Iowa City, IA 52242
  36. GENETIC CHARACTERIZATION OF CAFFEINE DEGRADATION via N-DEMETHYLATION BY PSEUDOMONAS PUTIDA CBB5
    Ryan M. Summers, Michael Louie, Chi Li Yu, Kailin C. Louie and Mani Subramanian*
    Department of Chemical and Biochemical Engineering, College of Engineering, The University of Iowa, Iowa City, IA 52242 and Center for Biocatalysis and Bioprocessing, The University of Iowa Research Park, Coralville, IA 52241
  37. INVESTIGATING THE MECHANISM OF HEPATOCYTE INVASIAN BY MALARIA-CAUSING PLASMODIA BY DESIGNING AND SYNTHESIZING CHEMICAL PROBES
    Tyrell R. Towle and Robert J. Kerns*
    Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  38. INHIBITION AND PROTEIN MODIFICATION OF GAPDH BY THE ENDOGENOUS NEUROTOXIN-3,4-DIHYDROXYPHENYLACETALDEHYDE
    Brigitte C. Vanle, Virginia Florang and Jonathan A. Doorn*
    Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  39. THE ROLE OF ENZYME DYNAMICS IN THYMIDYLATE SYNTHASE CATALYZED REACTION: A COMBINED EXPERIMENTAL - THEORETICAL APPROACH
    Zhen Wang1, Vicent Moliner2,3 and Amnon Kohen1*
    1Department of Chemistry, College of Liberal Arts and Sciences, The University of Iowa, Iowa City, IA 52242
    2Department de Química Física i Analítica, Universitat Jaume I, 12071 Castellón, Spain
    3Institute of Applied Radiation Chemistry, Technical University of Lodz, 90-924 Lodz, Poland
  40. NOVEL ANTIMUTANT C-7 ARYL FLUOROQUINOLONES
    Benjamin H. Williamson, Heidi A. Schwanz and Robert J. Kerns*
    Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, IA 52242
  41. APPROACHES TO SYNTHESIS OF THE STELLETTINS
    Veronica S. Wills and David F. Wiemer*
    Department of Chemistry, College of Liberal Arts and Sciences, The University of Iowa, Iowa City, IA 52242
  42. MODULAR AND EXPANDABLE DETECTION PLATFORM FOR CURRENT AND POTENTIAL FOOD TOXINS AND ADULTERANTS: SCREENING AND IDENTIFICATION OF MICROORGANISMS CONTAINING RICININE NITRILASE ACTIVITY
    Chi Li Yu1, Bhavita R. Bhatt1, Michael Sadowsky2, Lawrence P. Wackett2 and Mani Subramanian1*
    1Department of Chemical and Biochemical Engineering, College of Engineering, The University of Iowa, Iowa City, IA 52242 and Center for Biocatalysis and Bioprocessing, The University of Iowa Research Park, Coralville, IA 52241
    2Department of Biochemistry, The University of Minnesota, St. Paul, MN 55108
  43. CONTINUOUS NEAR INFRARED MONITOR FOR PICHIA PASTORIS BIOREACTORS
    Elizabeth R. Gibson1, Ed Koerperick1, Kaylee Lanz1, Jonathon T. Olesberg1,2, Gary W. Small1,2 and Mark A. Arnold1,2
    1ASL Analytical, Inc., Coralville, IA 52241
    2Optical Science and Technology Center and Department of Chemistry, College of Liberal Arts and Sciences, The University of Iowa, Iowa City, IA 52242
  44. CONTINUOUS PROTEIN PURIFICATION USING SIMULATED MOVING BED: TAKING THE CHROMATOGRAPHY PLATFORM TO THE NEXT LEVEL
    Anthony Grabski, Bruce Thalley, Alla Zilberman and Robert Mierendorf
    Semba Biosciences, Inc., Madison, WI 53719

POSTER PREPARATION

(1) The poster board has a 44" H x 68" W area for mounting the posters.
(2) Lettering and illustrations on the poster pages must be large enough to be read by attendees from a distance of 3 feet or more.
(3) Each poster must have a title, authors and affiliation section at the beginning. Material should be displayed in logical sequence (e.g., introduction, objectives, results, conclusion) and each sheet should be numbered.
(4)

Authors are responsible for mounting their own poster material on poster boards which will be provided at the conference. The Center will provide a reasonable supply of clear push pins. Posters should be removed immediately following the poster session and before dinner, since the poster boards are scheduled to be removed for use elsewhere.

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