Advanced Organic Chemistry - Chem 004:172 (Fall
2007)
Announcements
8/17/07
Wecome to 4:172.
12/19/07
Our 4:172 exam will take place on Friday, December 21st, 7:30 - 9:30 am, in S207 PBB.
Good luck!
12/20/07
Final Review
Coverage: Ch. 1-6
No. of questions: 7-8
Types of questions: multiple choice and short answer
Emphasis: Although ALL material that we covered in class is relevant to
our final exam, you can emphasize/deemphasize the following from each
chapter:
Ch. 1: Chemical Bonding and Molecular Structure
- types of bonding (e.g. hybridization, molecular orbitals, PMO)
Ch. 2: Stereochemistry, Conformation, and Stereoselectivity
- stereochemistry (e.g. stereogenic centers, stereospecific, stereoselective)
- less emphasis on specific conformations of acyclic and cyclic molecules
Ch. 3: Structural Effects on Stability and Reactivity
- thermodynamics and kinetics
- reaction/energy diagrams
- kinetic isotope effects
- linear free energies
Ch. 4: Nucleophilic Substitutions
- SN1 and SN2 reactions
- nucleophilicity (characteristics, leaving groups, conjugation)
- carbocations (e.g. factors affecting stability, nonclassical)
Ch. 5 Polar Addition and Elimination Reactions
- types of mechanisms
- stereochemistries
- less emphasis on eliminations
Ch. 6 Carbanions and Other Carbon Nucleophiles
- acidities of hydrocarbons
- stabilization by functional groups
- organometallic derivatives