Pharmacokinetics and Biopharmaceutics (46:138)

Reading Assignments for Dr. Svensson’s Lectures

 

 

Determinants of Pharmacologic Effect

Reading: Rowland and Tozer -  p. 1-17, 53-65, 203-211

Problems: p. 17 - #1 and 3; p. 65 - #1-3

 

Passage of Xenobiotics Across Biological Membranes

Reading: Rowland and Tozer – Chapter 8

Problems: p. 117 - #1-3

 

Effect of Route of Administration on Drug Disposition and Action

Reading: Washington, et al – p. 19-29, 166-174,

                Rowland and Tozer – p. 119-134

Problems: Rowland and Tozer – p. 135, #1, 2 & 5

 

Distribution of Xenobiotics

Reading: Rowland and Tozer – p. 137-152

Problems: p. 153 - #1

 

Pharmacogenetics

Reading: Rowland and Tozer – p. 221-228

Problems: p. 228 - #1-4

 

Noncompartmental Pharmacokinetics

Reading: Rowland and Tozer Appendix I-A & I-D

Problems #1, 2, & 4, p. 472.

 

Hepatic Clearance

Reading: Rowland and Tozer p. 156-169, 184-197

Problems #2 & 4, p. 197.

 

Metabolite Kinetics

Reading: Rowland and Tozer – Chapter 21

Problems: p. 390-392 - #2, 3, 7 & 9

 

Pharmacokinetic Drug Interactions

Reading: Rowland and Tozer Chapter 17

Problems #1-5, p. 284-286.

 

Dose- and Time-Dependent Pharmacokinetics

Reading: Rowland and Tozer Chapter 22

Problems #1-6, p. 418-423.

 

You are expected to know the material covered in the readings. The problems listed are designed to supplement the problems in the Lecture Tutorials and are provided for those students wishing additional problems to test their knowledge of the covered material.

 

Return to Pharmacokinetics and Biopharmaceutics Homepage