Answer to Practice Problem #4 for Effect of Route of Administration on Xenobiotic Disposition & Action Tutorial:

 

False. As discussed in class (using the example of chloramphenicol), some poorly soluble drugs are administered intravenously in the form of prodrugs. Hydrolysis of the prodrug, giving rise to the parent drug, may be incomplete - resulting in less than 100% bioavailability. 

 

Last revised 07/17/04

 

ã 2004 -  Craig K. Svensson, Pharm.D., Ph.D.

 

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