Time Course of Testosterone Action

 

Non-transcriptionally mediated

Seconds to minutes

Mitochondrial effects

Neurotransmitter release

Receptor binding

DNA binding

Transcriptionally mediated effects

Minutes to hours

Change in transcription rates

mRNA transit to cytoplasm

Synthesis of enzymes, serum proteins, androgen receptors
Hours to days

Altered metabolism

Altered serum proteins

Cellular architecture

Modulation of other receptors  

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