CURRENT TOPICS IN RADIATION AND CANCER BIOLOGY (77:548)

The University of Iowa

Fall 2005

11:30-12:30, Mondays

Room B180, Med Labs

Contact: nukhet-aykin-burns@uiowa.edu Tel 319-335-8025

 


August 22, 2005
Presenter: Dr. Domann
Paper: Schriner SE, Linford NJ, Martin GM, et al. (2005) Extension of Murine Lifespan by Overexpression of Catalase Targeted to Mitochondria. Science. 308(5730):1909-1911.[DOI Article]

August 29, 2005
Presenter: Disha Dayal
Paper: Behrend L, Mohr A, Dick T, Zwacka RM, et al. (2005) Manganese Superoxide Dismutase Induces p53-Dependent Senescence in Colorectal Cancer Cells. Mol Cell Biol. 25(17):7758-69.[DOI Article]

September 5, 2005
Presenter: Labor Day, no journal club.

September 12, 2005
Presenter: Sarita Menon
Paper: Chen C and Dickman MB. (2005) Proline suppresses apoptosis in the fungal pathogen Colletotrichum trifolii. PNAS 102(9):3459-3464.[DOI Article]

September 19, 2005
Presenter: Kjerstin Owens
Paper: Selak MA, Armour SM, MacKenzie ED, et al. (2005) Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. Cancer Cell. 7(1):77-85.[DOI Article]

September 26, 2005
Presenter: Tanja Hadzic
Paper: Kujoth GC, Hiona A, Pugh TD, et al. (2005) Mitochondrial DNA Mutations Oxidative Stress, and Apoptosis in Mammalian Aging. Science. 309:481-484.[DOI Article]

October 3, 2005
Presenter: Changbin Du
Paper: Toulany M, Dittmann K, Kruger M, et al. (2005) Radioresistance of K-Ras mutated human tumor cells is mediated through EGFR-dependent activation of PI3K-AKT pathway. Radiother Oncol. 76(2):143-50.[DOI Articl]

October 10, 2005
Presenter: Annie Liu
Paper: Husbeck B, Peehl DM, Knox SJ. (2005) Redox modulation of human prostate carcinoma cells by selenite increases radiation-induced cell killing. Free Radic Biol Med. 38(1):50-7.[DOI Articl]

October 17, 2005
Presenter: Radiation Research Society Conference, No journal club.

October 24, 2005
Presenter: Kelly Andringa
Paper: Taniguchi T, Tischkowitz M, Ameziane N, et al. (2003) Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med. 9(5):513-4.[DOI Article]

November 1, 2005
Presenter: Dr. Prabhat Goswami
Paper: Hu R-G, Sheng J, Qi X, et al. (2005) The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators. Nature 437:981-986.[DOI Article]

Paper: Lee MJ, Tasaki T, Moroi K, et al. (2005) RGS4 and RGS5 are in vivo substrates of the N-end rule pathway. PNAS 102:15030-15035.[DOI Article]

November 7, 2005
Presenter: Dr. Nukhet Aykin-Burns
Paper: Yin S, Li X, Meng Y, et al. (2005) Tumor suppressive maspin regulates cell response to oxidative stress by direct interaction with glutathione S-transferase. J Biol Chem. 280(41):34985-96.[DOI Article]

November 14, 2005
Presenter: Dr. Prabhat Goswami
Paper: Goessel G, Quante M, Hahn WC, et al. (2005) Creating oral squamous cancer cells: A cellular model of oral-esophageal carcinogenesis. Proc Natl Acad SCI. 102(43):15599-604.[DOI Article]

November 21, 2005
Presenter: No journal club, Thanksgiving

November 28, 2005
Presenter: Michael Hitchler
Paper: Thelwall PE, Yemin AY, Gillian TL, et al. (2005) Noninvasive in vivo detection of glutathione metabolism in tumors. Cancer Res. 65(22):10149-53.[DOI Article]

December 5, 2005
Presenter: Zhen Gao
Paper: Niida H, Tsuge S, Katsuno Y, et al. (2005) Depletion of Chk1 Leads to Premature Activation of Cdc2-cyclin B and Mitotic Catastrophe. J Biol Chem. 280(47):39246-52.[DOI Article]