Free Radical Journal Club

The University of Iowa

Spring 1998

12:00-1:00, Wednesdays

Room B180, Med Labs

Contact: garry-buettner@uiowa.edu Tel 319/335-6749

 

January 14, 1998
Presenter: Michael McCormick, PhD
Paper: Ehrt S. et al. (1997) A novel antioxidant gene from Mycobacterium tuberculosis. J Exp Med 186:1885-1896.

January 21, 1998
Presenter: Freya Schafer, PhD
Paper: Sies H. et al. (1997) Glutathione Peroxidase Protects against Peroxinitrite-mediated oxidations. J Biol Chem 272:27812-27817.

January 28, 1998
Presenter: Garry Buettner, PhD
Paper: Ghagourifar P, Richter C. (1997) Nitric oxide synthase activity in mitochondria. FEBS Lett 418: 291-296.

February 04, 1998
Presenter: Brett Wagner, MS
Paper: Lin et al. (1997) Reactive oxygen species participate in peroxynitrite-induced apoptosis in HL-60 cells. Biochem Biophys Res Comm 230: 115-119

February 11, 1998
Presenter: Shawn Flanagan, PhD.
Paper: Francis, Jonathan et al. (1997) Postischemic infusion of Cu/Zn Superoxide Dismutase or SOD: Tet 451 reduces cerebral infarction following focal ischemia/reperfusion in rats. Experimental Neurology 146: 435-443.
 
Kondo, Takeo et al. (1997) Reduction of CuZn-Superoxide Dismutase Activity Exacerbates Neuronal Cell Injury and Edema Formation after Transient Focal Cerebral Ischemia. Journal of Neuroscience 17 (11): 4180-4189.

February 18, 1998
Presenter: Larry Oberley, PhD.
Paper: Jin et al. (1997) Regulatory Role for a Novel Human Thioredoxin Perioxidase in NF-kB Activation. Journal of Biological Chemistry 272: 30952-30961.

February 25, 1998
Presenter: Meredith Preuss
Paper: D. C. Hooper et al. (1998) Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalomyelitis and multiplesclerosis. PNAS 95:675-680.

March 04, 1998
Presenter: Bode Olakanmi, PhD.
Paper: Chinmay, K et al. (1998) Role of ceruloplasmin in cellular iron uptake. Science 279: 714-717.

March 11, 1998
Presenter: Ying Zhang
Paper: Kwong, LK and Sohal, RS (1998) Substrate and site specificity of hydrogen peroxide generation in mouse mitochondria. Arch Biochem Biophys 350: 118-126.

March 18, 1998
No presentation: Spring Break

March 25, 1998
Presenter: Hong Wang
Paper: Foresti et al. (1997) Thiol compounds interact with nitric oxideregulating heme oxygenase-1 induction in endothelial cells. J Biol Chem 272: 18411-18417.

April 01, 1998
Presenter: Eric Kelley
Paper: Ambs et al. (1998) Frequent nitric oxide synthase-2 expression human colon adenomas: Implication for tumor angiogenesis and colon cancer progression. Cancer Research 58: 334-341.

April 08, 1998
Presenter: Jiqin Yang
Paper: Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW. (1997) Oncogene ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88:593-602.

April 15, 1998
Presenter: Stephen Hempel, MD
Paper: Mayer B, Pfeiffer S, Schrammel A, Koesling D, Schmidt K, Brunner F. (1998) A new pathway of nitric oxide/cyclic GMP signaling involving S-nitrosoglutathione.J Biol Chem 273:3264-3270.

April 22, 1998
Presenter: Yuping Zhang
Paper: Vecchini F, Pringault E, Billiar TR, Geller DA, Hausel P, Felley-Bosco E. (1997) Decreased activity of inducible nitric oxide synthase type 2 and modulation of the expression of glutathione S-transferase a, bcl-2, and metallothioneins during the differentiation of CaCo-2 cells. Cell Growth & Differentiation 8:261-268.

May 06, 1998
Presenter: Weiling Zhao
Paper: Pagano PJ. et al. (1997) Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: Enhancement by angiotension II. PNAS 94:14483-8.

May 13, 1998
Presenter: Tao Yan, PhD
Paper: Kang SW, Chae HZ, Seo MS, Kim K, Baines IC, and Rhee SG. (1998) Mammalian Peroxiredoxin Isoforms Can Reduce Hydrogen Peroxide Generated in Response to Growth Factors and Tumor Necrosis Factor-a. J. Biol. Chem. 273: 6297-6302.

May 20, 1998
Presenter: Heather Adu-Sarkodie, DDS.
Paper: Johnson TM, Yu Z-X, Ferrans VJ, Lowenstein RA, and Finkel T. (1996) Reactive oxygen species are downstream mediators of p53-dependent apoptosis. PNAS 93: 11848-11852.

May 27, 1998
Presenter: Freya Schafer, PhD
Paper: Zheng M; Aslund F; Storz G. (1998) Activation of the OxyR transcription factor by reversible disulfide bond formation. Science 279: 1718-1721.