Free Radical Journal Club

The University of Iowa

Fall 2003

12:00-1:00, Wednesdays

Room B180, Med Labs

Contact: garry-buettner@uiowa.edu Tel 319/335-6749

 

Presentations for Fall 2003:

August 27, 2003
Presenter:  Kelly Andringra
Paper:  Knowles HJ, Raval RR, Harris AL, Ratcliffe PJ. (2003) Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells. Cancer Res. 63:1764-1768.

September 3, 2003
Presenter: Dr. Buettner
Paper:  Zhao R, Masayasu H, Holmgren A. (2002) Ebselen: A substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant. PNAS  99:8579-8584.

September 10, 2003
Presenter: Jingru Liu
Paper:  Li J, Holbrook NJ. (2003) Common Mechanisms for Declines in Oxidative Stress Tolerance and Proliferation with Aging. Free Radical Biology & Medicine 35:292-299.

September 17, 2003
Presenter: Hualei Li
Paper:  Taillé C, Almolki A, Benhamed M, Zedda C, Mégret J, Berger P, Lesèche G, Fadel E, Yamaguchi T, Marthan R, Aubier M, Boczkowski J. (2003) Heme Oxygenase Inhibits human Airway Smooth Muscle Proliferation via a Bilirubin-dependent Modulation of ERK1/2 Phosphorylation. J. of Biol. ; Chem. 278:27160-27168.

September 24, 2003
Presenter: Carolyn Fisher
Paper:  Kurien BT, Scofield RH. (2003) Free radical mediated peroxidative damage in systemic lupus erythematosus. Life Sciences 73:1655-1666.

October 1, 2003
Presenter: Ehab H. Sarsour
Paper:  Harris N, Costa V, MacLean M, Mollapour M, Moradas-Ferreira P, Piper P. (2003) MnSOD Overexpression Extends the Yeast of Chronological (G0) Life Span but Acts Independently of Sir2p Histone Deacetylase to Shorten the Replicative Life Span of Dividing Cells. Free Radical Biology & Medicine 34:1599-1606.

October 8, 2003
Presenter:  Ben Slane
Paper:  Taylor ER, Hurrell F, Shannon RJ, Lin T-K, Hirst J, Murphy MP. (2003) Reversible Glutathionylation of Complex I Increases Mitochondrial Superoxide Formation. J. of Biol. Chem. 278:19603-19610.

October 15, 2003
Presenter: Dr. Goswami
Paper:  Akool E-S, Kleinert H, Hamada FMA, Abdelwahab MH, Förstermann U, Pfeilschifter J, Eberhardt W. (2003) Nitric Oxide Increases the Decay of Matrix Metalloproteinase 9 mRNA by Inhibiting the Expression of mRNA- stabilizing Factor HuR. Molecular and Cellular Biology 23:4901-4916.

October 22, 2003
Presenter: Kim Krager
Paper:  Emerson JP, Coulter ED, Phillips RS, Kurtz DM Jr. (2003) Kinetics of the Superoxide Reductase Catalytic Cycle. J. of Biol. Chem. 278:39662-39668.

October 29, 2003
Presenter:  Zhen Gao
Paper:  Sauer H, Wefer K, Vetrugno V, Pocchiari M, Gissel C, Sachinidis A,   Hescheler J, Wartenberg M. (2003) Regulation of Intrinsic Prion Protein by Growth Factors and TNF-α:  The Role of Intracellular Reactive Oxygen Species. Free Radical Biology & Medicine 35:586-594.

November 5, 2003
Presenter:  Christin Weydert
Paper: Rebrin I, Kamzalov S, Sohal RS. (2003) Effects of Age and caloric Restriction on Glutathione Redox State in Mice. Free Radical Biology & Medicine 35:626-635.

November 12, 2003
Presenter:  Gang Niu
Paper: Han D, Canali R, Rettori D, Kaplowitz N. (2003) Effect of Glutathione Depletion on Sites and Topology of Superoxide and Hydrogen Peroxide Production in Mitochondria. Molecular Pharmacology 64:1136-1144.

November 19 and 26, 2003
NO MEETING

December 3, 2003
Presenter: Haris Hamsakutty
Paper:  Dennery PA, Visner G, Weng Y-H, Nguyen X, Lu, F, Zander D, Yang G. (2003) Resistance to Hyperoxia with Heme Oxygenase-1 Disruption: Role  of Iron. Free Radical Biology & Medicine 34:124-133.

December 10, 2003
Presenter: Nükhet Aykins-Burns
Paper: Suh JH, Heath S-H, Hagen TM. (2003) Two Subpopulations of Mitochondria in the Aging Rat Heart Display Heterogenous Levels of Oxidative Stress. Free Radical Biology & Medicine 35:1064-1072.