Free Radical Journal Club

The University of Iowa

Spring 2004

12:00-1:00, Wednesdays

Room B180, Med Labs

Contact: garry-buettner@uiowa.edu Tel 319/335-6749

 

Presentations for Spring 2004

January 22, 2003
Presenter: Garry R. Buettner, Ph.D. 
Paper: Watson WH, Pohl J, Montfort WR, Stuchlik O, Reed MS, Powis G, Jones DP (2003) Redox potential of human thioredoxin 1 and identification of a second dithiol/disulfide motif. J Biol Chem. 278(35):33408-33415. Located at
 http://www.jbc.org/cgi/reprint/278/35/33408
January 28

Presenter: Kelly Andringa
Paper: DeHaan JB, Bladier C, Lotfi-Miri M, Taylor J (2003) FIBROBLASTS DERIVED FROM Gpx1 KNOCKOUT MICE DISPLAY SENESCENT-LIKE FEATURES AND ARE SUSCEPTIBLE TO H2O2-MEDIATED CELL DEATH. Free Radic Biol. & Med. 36(1):53-64.
Located Here

February 4
Presenter: Christine Weydert
Paper: Wheeler MD, Smutney OM, Samulski RJ. Secretion of extracellular superoxide dismutase from muscle transduced with recombinant adenovirus inhibits the growth of B16 melanomas in mice. Mol Cancer Res. 2003 Oct; 1(12): 871-881. Location: http://mcr.aacrjournals.org/cgi/reprint/1/12/871.pdf

February 11
Presenter: Dr. Juan Du
Papers: Mateo J, Garcia-Lecia M, Cadenas S (2003) Regulation of hypoxia-inducible factor-1? by nitric oxide through mitochondria-dependent and –independent pathways. Biochem. J. 376:537-544. Murphy M (2003) Commentary Does interplay between nitric oxide and mitochondria affect hypoxia-inducible transcription factor-1 activity? Biochem. J. 376:e5-e6.
Found at http://www.biochemj.org/bj/376/0537/3760537.pdf
Found at http://www.biochemj.org/bj/376/e005/376e005.pdf

February 18 Presenter: Aliye Uc
Paper: Morse D, Pischke SE, Zhou Zhihong (2003) Suppression of Inflammatory Cytokine Production by Carbon Monoxide Involves the JNK Pathway and AP-1. J. of Biol. Chem. 278(39):36993-36998.
Found at http://www.jbc.org/cgi/reprint/278/39/36993

February 25
Presenter: Sultana Banulescu
Paper: Brar S, Corbin Z, Kennedy T (2003) NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells. Am. J. Physiol. Cell Physiol. 285:C353-C369.
Found at http://ajpcell.physiology.org/cgi/reprint/285/2/C353.pdf

March 3
Presenter: Dr. Nukhet Aykin-Burns
Paper: Shertzer HG, Clay CD, Genter MB (2003) Uncoupling-mediated generation of reactive oxygen by halogenated aromatic hydrocarbons in mouse liver microsomes. J. Free Rad. Biomed. 36(5):618-631.
Located Here

March 31
Presenter: Dr. Goswami
Paper: Park H-S et al. (2004) Inhibition of apoptosis signal-regulating kinase 1 by nitric oxide through a thiol redox mechanism. J. Biol. Chem. 279(9):7584-7590. Found Here

April 7
Presenter: Dr. Larry Oberley
Paper: Davis CA, Hearns AS, Fletcher B et al. (2004) Potent anti-tumor effects of an active site mutant of human manganese-superoxide dismutase. J. Biol. Chem. 279(13):12769-12776. Found Here

April 14
Presenter: Jingru Liu
Paper: Park SY, Chang I, Kim J-Y et al. (2004) Resistance of Mitochondrial DNA-depleted Cells against Cell Death: ROLE OF MITOCHONDRIAL SUPEROXIDE DISMUTASE
J. Biol. Chem. 279:7512-520.
Found Here

April 21
Presenter: Ling Xiao
Paper: Hussain SP, Amstad P, He P et al. p53-Induced Up-Regulation of MnSOD and GPx but not Catalase Increases Oxidative Stress and Apoptosis. Cancer Res. 64:2350-2356.
Found at: http://cancerres.aacrjournals.org/cgi/reprint/64/7/2350.pdf

April 28
Presenter: Sharon Hu
Paper: Fielld LS, Furukawa Y, O’Halloran TV. (2003) Factors Controlling the Uptake of Yeast Copper/Zinc Superoxide Dismutase into Mitochondria.
J. Biol. Chem. 278:28052-28059.
Found Here

May 5
Presenter: Dr. Ken Dornfeld
Paper: Huang, ME et al (2003) A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations.
PNAS 100(20):11529-34.
http://www.pnas.org/cgi/reprint/100/20/11529.pdf