Free Radical Journal Club

The University of Iowa

Fall 2009

12:00-1:00, Wednesdays

Room B180, Med Labs

Contact: Tel 319/335-6749


August 26, 2009
Presenter: Dr. Garry Buettner
Paper:  Cardoso LA, Ferreira ST, Hermes-Lima M. (2008) Reductive inactivation of yeast glutathione reductase by Fe(II) and NADPH. Comp Biochem Physiol A Mol Integr Physiol. 2008 Nov;151(3):313-21.
Found at: [DOI Article]

September 2, 2009
Presenter: Jennifer Nickerson-Gass
Paper:Mitra K, Wunder C, Roysam B, Lin G, Lippincott-Schwartz J. (2009) A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase. Proc Natl Acad Sci U S A. 106(29):11960-5.
Found at [DOI Article]

September 9, 2009
Presenter: Yueming Zhu
Paper: Plecitá-Hlavatá L, Jezek J, Jezek P. Pro-oxidant mitochondrial matrix-targeted ubiquinone MitoQ10 acts as anti-oxidant at retarded electron transport or proton pumping within Complex I. Int J Biochem Cell Biol. 41(8-9):1697-707.
Found at:  [DOI Article]

September 16, 2009
Presenter:      Dr. Frederick Domann
Paper: Schafer ZT, Grassian AR, Song L, Jiang Z, Gerhart-Hines Z, Irie HY, Gao S, Puigserver P, Brugge JS. (2009) Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment. Nature. 461(7260):109-13.
Found at: [DOI Article]

September 23, 2009
Presenter: Adam Case
Paper: Niethammer P, Grabher C, Look AT, Mitchison TJ. (2009) A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish. Nature. 459(7249):996-9.
Found at: [DOI Article]

September 30, 2009
Presenter:Jim Jacobus
Paper:  Block K, Gorin Y, Abboud HE. (2009) Subcellular localization of Nox4 and regulation in diabetes. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14385-90.
Found at: [DOI Article]

October 7, 2009
Presenter: Tony Cyr
Paper: Gusarov, I, Shatalin, K, Starodubtseva, M, Nudler, E. Endogenous nitric oxide protects bacteria against a wide spectrum of antibiotics. (2009) Science 325:5946 p 1380-1384.
Found at: [DOI Article]

October 14, 2009
Presenter: Weipeng Bian
Paper: Parmigiani RB, Xu WS, Venta-Perez G, Erdjument-Bromage H, Yaneva M, Tempst P, Marks PA. (2008) HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation. Proc Natl Acad Sci U S A. 105(28):9633-8.
Found at:   [DOI Article]

October 21, 2009
Presenter:  canceled in it’s place is a FRJC 2009.10.21 SFRBM Webinar

October 28, 2009
Presenter: Jordan Witmer
Paper: Kyung Jin Junga, Eun Kyeong Leea, Byung Pal Yub, and Hae Young Chunga, (2009) Significance of protein tyrosine kinase/protein tyrosine phosphatase balance in the regulation of NF-κB signaling in the inflammatory process and aging. Free Radical Biology and Medicine 47(7):983-991.
Found at:[DOI Article]

November 4, 2009
Presenter:      Janice Wang
Paper:  Eisenberg T, Knauer H, Schauer A, Büttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L, Hartl R, Schraml E, Criollo A, Megalou E, Weiskopf D, Laun P, Heeren G, Breitenbach M, Grubeck-Loebenstein B, Herker E, Fahrenkrog B, Fröhlich KU, Sinner F, Tavernarakis N, Minois N, Kroemer G, Madeo F. (2009) Induction of autophagy by spermidine promotes longevity. Nat Cell Biol. Epub ahead of print].
Found at: [DOI Article]

November 11, 2009
Presenter: Josh Madsen
Paper: Zid BM, Rogers AN, Katewa SD, Vargas MA, Kolipinski MC, Lu TA, Benzer S, Kapahi P. (2009) 4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila. Cell. 139(1):149-60.
Found at: [DOI Article]

November 18, 2009
Presenter:      No FRJC, SFRBM Annual Meeting

November 25, 2009
Presenter:      No Presenter, Thanksgiving Week

December 2, 2009
Presenter:      Lauren Wegman
Paper: Shi DY, Xie FZ, Zhai C, Stern JS, Liu Y, Liu SL. (2009) The role of cellular oxidative stress in regulating glycolysis energy metabolism in hepatoma cells. Mol Cancer. 8:32.
Found at: [DOI Article]

December 9, 2009
Presenter: Mitch Coleman
Paper: Jiang J, Stoyanovsky DA, Belikova NA, Tyurina YY, Zhao Q, Tungekar MA, Kapralova V, Huang Z, Mintz AH, Greenberger JS, Kagan VE. (2009) A mitochondria-targeted triphenylphosphonium-conjugated nitroxide functions as a radioprotector/mitigator. Radiat Res. 172(6):706-17.
Found at:  [DOI Article]