Free Radical Journal Club

The University of Iowa

Fall 2010

12:00-1:00, Wednesdays

Room B180, Med Labs

Contact: garry-buettner@uiowa.edu Tel 319/335-6749

 

December 8, 2010
Presenter: Garry R. Buettner
Paper: Chakravarti R, Aulak KS, Fox PL, Stuehr DJ. (2010) GAPDH regulates cellular heme insertion into inducible nitric oxide synthase. Proc Natl Acad Sci U S A. 107(42):18004-9. PMID: 20921417

August 25, 2010
Presenter: Tony Cyr
Paper: Bao J, Scott I, Lu Z, Pang L, Dimond CC, Gius D, Sack MN. (2010) SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity. Free Radic Biol Med. [Epub ahead of print]

September 1, 2010
Presenter: Dr. Prabhat Goswami
Paper: Mesquita A, Weinberger M, Silva A, Sampaio-Marques B, Almeida B, Leão C, Costa V, Rodrigues F, Burhans WC, Ludovico P. (2010) Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H2O2 and superoxide dismutase activity. Proc Natl Acad Sci U S A. 107 (34):15123-15128

September 8, 2010
Presenter: Maneesh Kumar
Commentary Paper: Rubenstein EM, Schmidt MC. (2010) The glucose signal and metabolic p[H+]lux.
EMBO J. 29(15):2473-4.

Paper: Dechant R, Binda M, Lee SS, Pelet S, Winderickx J, Peter M. (2010) Cytosolic pH is a second messenger for glucose and regulates the PKA pathway through V-ATPase. EMBO J. 29(15):2515-26.

September 15, 2010
Presenter: Peter Scarbrough
Paper: Jobgen W, Meininger CJ, Jobgen SC, Li P, Lee MJ, Smith SB, Spencer TE, Fried SK, Wu G. (2009) Dietary L-arginine supplementation reduces white fat gain and enhances skeletal muscle and brown fat masses in diet-induced obese rats. J. Nutr. 139(2):230-237.

September 22, 2010
Presenter: Jordan Witmer
Paper: Romagnoli M, Gomez-Cabrera MC, Perrelli MG, Biasi F, Pallardó FV, Sastre J, Poli G, Viña J. (2010) Xanthine oxidase-induced oxidative stress causes activation of NF-kappaB and inflammation in the liver of type I diabetic rats. Free Radic Biol Med. 49(2):171-7.

September 29, 2010
Presenter: Dr. Burton B. Yang
Talk: "The role of microRNAs in tumorigenesis and angiogenesis"
** Note special time and place!

October 6, 2010
Presenter: Dr. Frederick Domann
Paper:  Racki LR, Yang JG, Naber N, Partensky PD, Acevedo A, Purcell TJ, Cooke R, Cheng Y, Narlikar GJ. (2009) The chromatin remodeller ACF acts as a dimeric motor to space nucleosomes. Nature. 462(7276):1016-21.

October 13, 2010
Presenter: Malvika Rawal
Paper: Garedew A, Henderson SO, Moncada S. (2010) Activated macrophages utilize glycolytic ATP to maintain mitochondrial membrane potential and prevent apoptotic cell death. Cell Death Differ. 2010 Oct;17(10):1540-50. Epub 2010 Mar 26.

October 20, 2010
Presenter: Gaowei Mao
Paper: Larbi A, Cabreiro F, Zelba H, Marthandan S, Combet E, Friguet B, Petropoulos I, Barnett Y, Pawelec G. (2010) Reduced oxygen tension results in reduced human T cell proliferation and increased intracellular oxidative damage and susceptibility to apoptosis upon activation. Free Radic Biol Med. 48(1):26-34.

October 27, 2010
Presenter: Dr. James Mezhir
Paper: Yao H, Arunachalam G, Hwang JW, Chung S, Sundar IK, Kinnula VL, Crapo JD, Rahman I. (2010)  Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM. Proc Natl Acad Sci USA. 107(35):15571-6

November 3, 2010
Presenter: Jim Jacobus
Paper:  Khutornenko AA, Roudko VV, Chernyak BV, Vartapetian AB, Chumakov PM, Evstafieva AG. (2010) Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway. Proc Natl Acad Sci U S A. 107(29):12828-33.

November 10, 2010
Presenter: Joost vant Erve
Paper:  Joost vant Erve
Paper: Gülden M, Jess A, Kammann J, Maser E, Seibert H. (2010) Cytotoxic potency of H2O2 in cell cultures: impact of cell concentration and exposure time. Free Radic Biol Med. 49(8):1298-305.

November 17, 2010
Presenter:      No FRJC, SFRBM Annual Meeting

November 24, 2010
Presenter:      No Presenter, Thanksgiving Week

December 1, 2010
Presenter:Dr. Joshua Madsen
Paper: Bungard D, Fuerth BJ, Zeng PY, Faubert B, Maas NL, Viollet B, Carling D, Thompson CB, Jones RG, Berger SL. (2010) Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. Science. 329(5996):1201-5.
PMID: 20647423