Free Radical Journal Club

The University of Iowa

Fall 2011

12:00-1:00, Wednesdays

Room B180, Med Labs

Contact: garry-buettner@uiowa.edu Tel 319/335-6749

 

August 29, 2011
Presenter:  Cameron Cushing
Paper:  Kuhn AM, Tzieply N, Schmidt MV, von Knethen A, Namgaladze D, Yamamoto M, Brüne B. (2011) Antioxidant signaling via Nrf2 counteracts lipopolysaccharide-mediated inflammatory responses in foam cell macrophages. FRBM. 50(10):1382-1391.  PMID: 21382476

September 12, 2011
Presenter:  Jaimee Eckers
Paper:  Speckmann B, Pinto A, Winter M, Förster I, Sies H, Steinbrenner H. (2010) Proinflammatory cytokines down-regulate intestinal selenoprotein P biosynthesis via NOS2 induction. Free Radic Biol Med. 49(5):777-85.  PMID: 20542496

September 26, 2011
Presenter: Malvika Rawal
Paper: Kim Y, Kim BH, Lee H, Jeon B, Lee YS, Kwon M-J, Kim T-Y. (2011) Regulation of skin inflammation and angiogenesis by EC-SOD via HIF-1alpha and NF-kappaB pathways. FRBM, unedited manuscript that has been accepted for publication.
DOI Link: http://dx.doi.org/10.1016/j.freeradbiomed.2011.08.027

October 10, 2011
Presenter: Wusheng Xiao
Paper:  Usuki F, Yamashita A, Fujimura M. (2011) Post-transcriptional defects of antioxidant selenoenzymes cause oxidative stress under methylmercury exposure. J Biol Chem. 286(8):6641-9.  PMID: 21106535

October 24, 2011
Presenter: Jennifer Hrabe
Paper: Lerner I, Hermano E, Zcharia E, Rodkin D, Bulvik R, Doviner V, Rubinstein AM, Ishai-Michaeli R, Atzmon R, Sherman Y, Meirovitz A, Peretz T, Vlodavsky I, Elkin M.
 Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice. J Clin Invest. 2011 May; 121(5):1709-21. PMID: 21490396  PMCID: PMC3083784

November 7, 2011
Presenter: Kelley Salem
Paper:  Morinaka A, Funato Y, Uesugi K, Miki H. Oligomeric peroxiredoxin-I is an essential intermediate for p53 to activate MST1 kinase and apoptosis. Oncogene. 2011 Oct; 30(40):4208-18. doi: 10.1038/onc.2011.139.  PMID:21516123

Presenter: Kyle Kloepping
Paper:  Ganguly SS, Fiore LS, Sims JT, Friend JW, Srinivasan D, Thacker MA, Cibull ML, Wang C, Novak M, Kaetzel DM, Plattner R. (2011) c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression. Oncogene. [Epub ahead of print]. PMID: 21892207.

November 21, 2011
Presenter: Thanksgiving week, no journal club

December 5, 2011
Presenter: Jess Welsh
Paper: Nandal A, Ruiz JC, Subramanian P, Ghimire-Rijal S, Sinnamon RA, Stemmler TL, Bruick RK, Philpott CC. Activation of the HIF Prolyl Hydroxylase by the Iron Chaperones PCBP1 and PCBP2. Cell Metab. 2011 Nov 2; 14(5):647-57. PMID: 22055506