Free Radical Journal Club

The University of Iowa

Fall 2013

12:00-1:00, Wednesdays

Room B180, Med Labs

Contact: garry-buettner@uiowa.edu Tel 319/335-6749

 

December 2, 2013
Presenter: Kelley Salem
Paper: Asensio-Lopez MC, Sanchez-Mas J, Pascual-Figal DA, de Torre C, Valdes M, Lax A. Ferritin heavy chain as main mediator of preventive effect of metformin against mitochondrial damage induced by doxorubicin in cardiomyocytes. Free Radic Biol Med. 2013 Nov 11;67C:19-29. doi: 10.1016/j.freeradbiomed.2013.11.003. [Epub ahead of print]
[DOI Link,http://dx.doi.org/doi:10.1016/j.freeradbiomed.2013.11.003

August 26, 2013
Presenter: Dr. Garry R. Buettner
Paper:  Bocedi A, Fabrini R, Farrotti A, Stella L, Ketterman AJ, Pedersen JZ, Allocati N, Lau PC, Grosse S, Eltis LD, Ruzzini A, Edwards TE, Morici L, Del Grosso E, Guidoni L, Bovi D, Lo Bello M, Federici G, Parker MW, Board PG, Ricci G. (2013) The Impact of Nitric Oxide Toxicity on the Evolution of the Glutathione Transferase Superfamily. A proposal for an evolutionary driving force. J Biol Chem. 288(34):24936-24047.
PMID: 23828197
http://dx.doi.org/10.1074/jbc.M113.476135

September 9, 2013
Presenter: Dr. Garry R. Buettner
Paper:  Ibrahim WH, Habib HM, Kamal H, St Clair DK, Chow CK. (2013) Mitochondrial superoxide mediates labile iron level: evidence from Mn-SOD-transgenic mice and heterozygous knockout mice and isolated rat liver mitochondria. Free Radic Biol Med. 65:143-149.  PMID: 23792772
http://dx.doi.org/10.1016/j.freeradbiomed.2013.06.026

Sept 23, 2012
Presenter: Dr. Douglas R. Spitz
Paper: Leadsham JE, Sanders G, Giannaki S, Bastow EL, Hutton R, Naeimi WR, Breitenbach M, Gourlay CW. (2013) Loss of Cytochrome c Oxidase Promotes RAS-Dependent ROS Production from the ER Resident NADPH Oxidase, Yno1p, in Yeast. Cell Metab. 2013 Aug 6;18(2):279-86. doi: 10.1016/j.cmet.2013.07.005.
[DOI Article]

October 7, 2011
Presenter: Garry R. Buettner
Paper: Liu C, Zhao W, Christ GJ, Gladwin MT, Kim-Shapiro DB. (2013) Nitric oxide scavenging by red cell microparticles. Free Radic Biol Med. 2013 Sep 16. doi:pii: S0891-5849(13)00605-9. 10.1016/j.freeradbiomed.2013.09.002. [Epub ahead of print]
PMID:  24051181 [Full Text Article]

Paper: Bohannon J. (2013) Who's Afraid of Peer Review? Science. 2013;342:6154:60-65.
[DOI Link]

October 21, 2013
Presenter: Dr. Prabhat C. Goswami
Paper: Zhang B, Davidson MM, Zhou H, Wang C, Walker WF, Hei TK. (2013) Cytoplasmic irradiation results in mitochondrial dysfunction and DRP1-dependent mitochondrial fission. Cancer Res. 2013 Sep 30. [Epub ahead of print] PMID: 24080278.
[Link]

November 4, 2013
Presenter: Dr. Ehab Sarsour
Paper: Velarde MC, Flynn JM, Day NU, Melov S, Campisi J. (2012) Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin. ng (Albany NY). 2012 Jan;4(1):3-12. PMID:22278880 PMCID:PMC3292901.
[Free Link]

November 18, 2013
Presenter: Jyungmean Son
Paper:  Houtkooper RH, Mouchiroud L, Ryu D, Moullan N, Katsyuba E, Knott G, Williams RW, Auwerx J.(2013) Mitonuclear protein imbalance as a conserved longevity mechanism. Nature. 2013 May 23;497(7450):451-7. doi: 10.1038/nature12188. PMID: 23698443.
[Link]