Free Radical Journal Club

The University of Iowa

Semester 2013

11:30-12:30 pm, Mondays

Room B180, Med Labs

Contact: garry-buettner@uiowa.edu Tel 319/335-6749


May 6, 2013
Presenter: Dr. Ehab Sarsour
Paper: Chae S, Ahn BY, Byun K, Cho YM, Yu MH, Lee B, Hwang D, Park KS. A systems approach for decoding mitochondrial retrograde signaling pathways. Science signaling. 2013;6(264):rs4. PMID: 23443683.
[DOI Article]

January 28, 2013
Presenter: Dr. Garry R. Buettner
Paper: Du Y, Zhang H, Lu J, Holmgren A. (2012)  Glutathione and glutaredoxin act as a backup of human thioredoxin reductase 1 to reduce thioredoxin 1 preventing cell death by aurothioglucose. J Biol Chem. 287(45):38210-38219. http://dx.doi.org/10.1074/jbc.M112.392225     PMID: 22977247 
[DOI Article]

February 11, 2013
Due to a scheduling conflict, the FRJC of Monday February 11 is  canceled.  The presentation is rescheduled for Feb 25.

We invite everyone to attend the Radiation Oncology Seminar for Physics Director Candidate:
Dr. Timothy Zhu, PhD, University of Pennsylvania, Dept. of Radiation Oncology, Perlman Center for Advanced Medicine.
Title: Photodynamic Therapy of Prostate Cancer
When: 12:00 pm in Rad Onc Conference Room 01600 PFP

February 25, 2013
Presenter: Dr. James Jacobus
Paper: Ansenberger-Fricano K, Ganini D, Mao M, Chatterjee S, Dallas S, Mason RP, Stadler K, Santos JH, Bonini MG. The peroxidase activity of mitochondrial superoxide dismutase. Free Radic Biol Med. 2013 Jan;54:116-24. doi: 10.1016/j.freeradbiomed.2012.08.573.
Epub 2012 Aug 28. PMID:22982047
[DOI Article]

March 11, 2013
Presenter: Malvika Rawal
Paper: DN, Bauer AJ, Cantley AM, Yang WS, Morrison B 3rd, Stockwell BR. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 2012 May 25;149(5):1060-72. doi: 10.1016/j.cell.2012.03.042. PMID:22632970
[DOI Article]

March 25, 2013
Presenter: Kelley Salem
Paper: Wang R, Liu C, Xia L, Zhao G, Gabrilove J, Waxman S, Jing Y. Ethacrynic acid and a derivative enhance apoptosis in arsenic trioxide-treated myeloid leukemia and lymphoma cells: the role of glutathione s-transferase p1-1. Clin Cancer Res. 2012 Dec 15;18(24):6690-701. doi: 10.1158/1078-0432.CCR-12-0770. Epub 2012 Oct 18.
[DOI Article]

April 8, 2013
Presenter: Dr. Prabhat C. Goswami
Paper: Huang PH, Chuang HC, Chou CC, Wang H, Lee SL, Yang HC, Chiu HC, Kapuriya N, Wang D, Kulp SK, Chen CS. Vitamin E Facilitates the Inactivation of the Kinase Akt by the Phosphatase PHLPP1. Sci Signal. 2013 Mar 19;6(267):ra19. doi: 10.1126/scisignal.2003816. PMID:23512990.
[DOI Article]

April 22, 2013
Presenter: Joost Thomas Van’t Erve
Paper: Alex George, Suvarnamala Pushkaran, Diamantis G. Konstantinidis, Sebastian Koochaki, Punam Malik, Narla Mohandas, Yi Zheng, Clinton H. Joiner, and Theodosia A. Kalfa. Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease. Blood. 2013 Mar 14;121(11):2099-107. doi: 10.1182/blood-2012-07-441188. PMID: 23349388
[DOI Article]