Amanda Kalen (Baker), BA

Department of Radiation Oncology
Free Radical and Radiation Biology
B180 Med Labs
The University of Iowa
Iowa City, IA 52242-1101, USA

Tel : 319-335-8025
Fax: 319-335-8039

E-mail: amanda-kalen@uiowa.edu

 

 

 

 

 

 

Lab

Goswami Lab

Publications

Zhu Y, Kalen AL, Li L, Lehmler HJ, Robertson LW, Goswami PC, Spitz DR, Aykin-Burns N. Polychlorinated-biphenyl-induced oxidative stress and cytotoxicity can be mitigated by antioxidants after exposure. Free Radic Biol Med. 2009; 47(12):1762-71. PMID: 19796678.

Du C, Gao Z, Venkatesha VA, Kalen AL, Chaudhuri L, Spitz DR, Cullen JJ, Oberley LW, Goswami PC Mitochondrial ROS and radiation induced transformation in mouse embryonic fibroblasts.Cancer Biol Ther. 2009; 8(20):1962-71. PMID: 19738419

Cloos CR, Daniels DH, Kalen A, Matthews K, Du J, Goswami PC, Cullen JJ. Mitochondrial DNA depletion induces radioresistance by suppressing G2 checkpoint activation in human pancreatic cancer cells.Radiat Res. 2009; 171(5):581-7. PMID: 19580493

Sarsour EH, Kumar MG, Chaudhuri L, Kalen AL, Goswami PC. Redox control of the cell cycle in health and disease.Antioxid Redox Signal. 2009; 11(12):2985-3011. PMID: 19505186

Sun W, Kalen AL, Smith BJ, Cullen JJ, Oberley LW. Enhancing the antitumor activity of adriamycin and ionizing radiation.Cancer Res. 2009; 69(10):4294-300. PMID: 19401447

Gao Z, Sarsour EH, Kalen AL, Li L, Kumar MG, Goswami PC. Late ROS accumulation and radiosensitivity in SOD1-overexpressing human glioma cells. Free Radic Biol Med. 2008; 45(11):1501-9. PMID: 18790046

Venkatesha VA, Venkataraman S, Sarsour EH, Kalen AL, Buettner GR, Robertson LW, Lehmler HJ, Goswami PC. Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells. Free Radic Biol Med. 2008; 45(8):1094-102. PMID: 18691649

Sarsour EH, Venkataraman S, Kalen AL, Oberley LW, Goswami PC. Manganese superoxide dismutase activity regulates transitions between quiescent and proliferative growth. Aging Cell. 2008; 7(3):405-17. PMID: 18331617

Sarsour EH, Venkataraman S, Kalen AL, Oberley LW, Goswami PC. Manganese superoxide dismutase activity regulates transitions between quiescent and proliferative growth. Aging Cell. 2008; 7(3):405-17. PMID: 18331617

Menon SG, Sarsour EH, Kalen AL, Venkataraman S, Hitchler MJ, Domann FE, Oberley LW, Goswami PC. Superoxide signaling mediates N-acetyl-L-cysteine-induced G1 arrest: regulatory role of cyclin D1 and manganese superoxide dismutase. Cancer Res. 2007; 67(13):6392-9. PMID: 17616699

Kalen AL, Sarsour EH, Venkataraman S, Goswami PC. Mn-superoxide dismutase overexpression enhances G2 accumulation and radioresistance in human oral squamous carcinoma cells. Antioxid Redox Signal. 2006; 8(7-8):1273-81. PMID: 16910775

Slane BG, Aykin-Burns N, Smith BJ, Kalen AL, Goswami PC, Domann FE, Spitz DR.
Mutation of succinate dehydrogenase subunit C results in increased O2.-, oxidative stress, and genomic instability. Cancer Res. 2006; 66(15):7615-20. PMID: 16885361

Delsite RL, Rasmussen LJ, Rasmussen AK, Kalen A, Goswami PC, Singh KK.
Mitochondrial impairment is accompanied by impaired oxidative DNA repair in the nucleus.
Mutagenesis. 2003; 18(6):497-503. PMID: 14614184

Schraw TD, Rutledge TW, Crawford GL, Bernstein AM, Kalen AL, Pessin JE, Whiteheart SW. Granule stores from cellubrevin/VAMP-3 null mouse platelets exhibit normal stimulus-induced release. Blood. 2003; 102(5):1716-22. PMID: 12738662