Transport Phenomnea in Physiological SystemsTime & Place:
Instructor:
Jun Ni, Ph.D., Associate Professor
Department of Radiology, Carver College of Medicine,
Biomedical Engineering
Mechanical Engineering
University of Iowa, Iowa City, IA, USA
Tel: (319) 335-9490
E-mail: jun-ni@uiowa.eduOffice Hours and Place:
Textbook:
George A. Truskey, Fan Yuan, David F. Katz , "Transport Phenomena in Biological System ," First Edition, Pearson Prentice Hall, 2004.
Class Lecture Notes:
Additional notes or handouts may be available in classroom.Course Description: this course addresses the issues of transport phenomna in biological and physiological systems. It presents engineering fundamentals and biological applications, and helps biomedical students learn how to develop and critically analyze models of biological transport and reaction processes. It course covers topics in fluid mechanics, mass transport, and biochemical interactions, with engineering concepts motivated by specific biological and physiological problems. The course is designed for graduate level biomedical students, and thermall science students who are interested in modeling and simulations of transport phenomena in biomedical systems.
Pre-requisites: TBD
Course Contents:
A. Introduction to Physiologicall Fluid Mechanics1. Introduction.
2. Conservation and Momentum Balances
3. Conservation Relations for Fluid Transport, Dimensional Analysis and Scaling
4. Macroscopic Form of Conservation Relations and Applications of Momentum Transport
5. Fluid Flow in the Circulation and Tissues
B. Fundamentals and Appplications of Mass Transport
6. Introduction to Mass Transport
7. Diffusion with Convection or Electrical Potentials
8. Transport in Porous Media
9. Transvascular Transport
10. Solvent and Solute Transport across the Kidney Glomerulus
C. Effect of Mass Transport Upon Biomedical Interactions
11. Mass Transport and Biochemical Interactions
12. Oxygen Transport from the Lungs to the Tissues
13. Ligand-Receptor Kinetics on the Cell Surface and Molecular Transport within Cells
14. Cell Adhesion and Cell Signaling
15. Transport of Drugs and Macromolecules in Tumors
16. Transport in Organs and Organisms
17. Heat Transfer in Biological Systems
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