Time & Place:
TBD
Instructor:
Jun Ni, Ph.D., Associate Professor
Department of Radiology, Carver College of Medicine,
Biomedical Engineering
Mechanical Engineering
University of Iowa, Iowa City, IA, USA
Tel: (319) 335-9490
E-mail: jun-ni@uiowa.edu
Office Hours and Place:
TBD
Textbook:
 Computational Cell Biology
An Introduction to Computer Modeling in Molecular Cell Biology
Fall, C.P.; Marland, E.S.; Wagner, J.M.; Tyson, J.J. (Eds.)
ISBN: 978-0-387-95369-4
Class Lecture Notes:
Additional notes or handouts may be available in classroom.
Course Description: this course covers an introduction to dynamic modeling in cell biology, emphasizing computational approaches based on realistic molecular mechanisms. It is designed to introduce cell biology and neuroscience students to computational modeling, and applied mathematics students, theoretical biologists, and engineers to many of the problems in dynamical cell biology. The course is for advanced undergraduate and graduate theoretical biologists, and for mathematics students and life scientists who wish to learn about modeling in cell biology.
Pre-requisites:
TBD
Course Contents:
Introductory
Dynamic Phenomena in Cells
Voltage Gated Ionic Currents
Transporters and Pumps
Fast and Slow time Scales
Whole Cell Models
Intercellular Communication
Advanced Material
Spatial Modeling
Modeling Intracellular Calcium Waves and Sparks
Biochemical Oscillations
Cell Cycle Controls
Modeling the Stochastic Gating of Ion Channels
Molecular Motors: Theory
Molecular Motors: Example
Numerical Algorithms
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