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Student Publications
 

Past and Current Student Papers Published or In Press - (program students are marked in bold):

  • Siemens D.R., Elzey B.D., Lubaroff D.M., Bohlken C., Jensen R.J., Swanson A.K., and Ratliff T.L. (2001) Restoration of the ability to generate CTL in mice immune to adenovirus by delivery of virus in a collagen-based matrix. J. Immunol. 166:731-735.

  • Lemke (Bohlken), C.D., Haynes, J.S., Spaete, R., Adolphson, D., Vorwald, A., Lager, K. and Butler, J.E. (2004) Lymphoid hyperplasia resulting in immune dysregulation is caused by porcine reproductive and respiratory syndrome virus infection in neonatal pigs. J. Immunol. 172: 1916-1925.

  • Brown, K.D., Hostager, B.S. and Bishop, G.A. (2001) Differential signaling and TRAF degradation mediated by CD40 and the EBV oncoprotein LMP1. J. Exp. Med. 193:943-954.

  • Brown, K.D., Hostager, B.S. and Bishop, G.A. (2002) Regulation of TRAF2 signaling by self-induced degradation. J. Biol. Chem. 277:19433-19438.

  • Bishop, G.A., Hostager, B.S. and Brown, K.D. (2002) Mechanisms of tumor necrosis factor receptor associated factor (TRAF) regulation in B lymphocytes. J. Leukoc. Biol. 72(1):19-23.

  • Crowther, J.E., Kutala, V.K., Kuppusamy, P., Ferguson, J.S., Beharka, A.A., Zweier, J.L., McCormack, F.X. and Schlesinger, L.S. (2004) Pulmonary surfactant protein A inhibits macrophage reactive oxygen intermediate production in response to stimuli by reducing NADPH oxidase activity. J. Immunol., 172:6866-6874.

  • Dandekar, A.A., Anghelina, D., and Perlman, S. (2004) Bystander T cell mediated demyelination is interferon-gamma dependent in a coronavirus model of multiple sclerosis. Am. J. Pathol. 164:363-369.

  • Dandekar, A.A. and Perlman, S. (2003) Axons and neurons in coronavirus induced demyelination. In: Expermental models of multiple sclerosis, E. Lavi, ed. (in press).

  • Dandekar, A.A., Jacobsen, G., Waldschmidt, T.J., Perlman, S. (2003) Antibody-mediated protection against cytotoxic T cell escape in coronavirus-induced demyelination. J. Immunol, J. Virol. 77:11867-11874..

  • Dandekar, A.A. and Perlman, S. (2002). Virus-induced demyelination in nude mice is mediated by gamma-delta T cells. Am. J. Pathol. (4):1255-63.

  • Wu, G., Dandekar, A., Pewe, L., and Perlman, S. (2000) CD4 and CD8 T cells have redundant but not identical roles in virus-induced demyelination. J. Immunol. 165:2278-2286.

  • Wu, G., Dandekar, A., Pewe, L., and Perlman, S. (2001) The role of CD4 and CD8 T cells in MHV-JHM-induced demyelination. Adv. Expt. Med. Biol., 494:341-7.

  • Dandekar, A.,Wu, G., Pewe, L., and Perlman, S. (2001) Axonal damage is T-cell mediated and occurs concomitantly with demyelination in mice infected with neurotropic coronavirus. J. Virol. 75:6115-6120.

  • Erickson, L.D., Tygrett, L.T., Bhatia, S.K., and Waldschmidt, T.J. (1996) Differential expression of CD22 (Lyb8) on murine B cells. Int. Immunol. 8:1121-1129.

  • Erickson, L.D. and Waldschmidt, T.J. (1998) T helper cell activation of B1 cells. Mucosal Immunology Update 6:10.

  • Erickson, L.D., Foy T.M., and Waldschmidt, T.J. (2001) Murine B1 B cells require IL-5 for optimal T cell-dependent activation. J. Immunol.166:1531-1539.

  • Fang, N., Motto, D.G., Ross, S.E., and Koretzky, G.A. (1996) Tyrosines 113, 128, and 145 of SLP-76 are required for optimal augmentation of NFAT promoter activity. J. Immunol. 157:3769-3773.

  • Peterson, E.J., Clements, J.L., Fang, N. and Koretzky, G.A. (1998) Adaptor proteins in lymphocyte antigen-receptor signaling. Curr. Opin. Immunol. 10:337-344.

  • Binstadt, B.A., Billadeau, D.D., Jevermovic, D., Williams, B.L., Fang, N., Yi, T., Koretzky, G.A., Abraham, R.T. and Leibson, P.J. (1998) SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors. J. Biol. Chem. 273: 27518-27523.

  • Liu, S.K., Fang, N., Koretzky, G.A., and McGlade, C.J. (1999) The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors. Current Biology 9:67-75.

  • Fang, N., and Koretzky, G.A. (1999) SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity. J. Biol. Chem. 274(23):16206-16212.

  • Gantt, K.R., Schultz-Cherry, S., Rodriguez, N., Jeronimo, S.M., Nascimento, E.T., Goldman, T.L., Recker, T.J., Miller, M.A., Wilson, M.E. (2003) Activation of TGF-beta by Leishmania chagasi: importance for parasite survival in macrophages. J Immunol. Mar 1;170(5):2613-20.

  • Gantt, K.R., Goldman, T.L., McCormick, M.L., Miller, M.A., Jeronimo, S.M., Nascimento, E.T., Britigan, B.E., and Wilson, M.E. (2001) Oxidative responses of human and murine macrophages during phagocytosis of Leishmania chagasi. J. Immunol. 167(2):893-901.

  • Miller, M.A., McGowan, S.E., Gantt, K.R., Champion, M., Novick, S.L., Andersen, K.A., Bacchi,
    C.J., Yarlett, N., Britigan, B.E., and Wilson, M.E. (2000) Inducible resistance to oxidant stress in the protozoan Leishmania chagasi. J. Biol. Chem. 275(43):33883-33889.

  • Hamilton. S.E., Porter, B.P., Messingham, K.A.N., Badovinac, V.P. and Harty, J.T. (2004) Class Ia-restricted memory T-cells inhibit expansion of a non-protective class Ib-(H2-M3)-restricted memory response. Nat. Immunol. 5:159-168.

  • Tvinnereim, A. R., Kolwyck, D., Hamilton, S.E. and Harty, J.T. (2004) Neutrophil involvement in cross-priming CD8+ T cell responses to bacterial antigens. Submitted.

  • Badovinac, V.P., Hamilton, S.E. and Harty, J.T. (2003) Viral infection results in massive CD8+ T cell expansion and mortality in vaccinated perforin-deficient mice. Immunity. 18:463-474.

  • Badovinac, V.P., Messingham, K.A.N., Hamilton, S.E. and Harty, J.T. (2003) Regulation of CD8+ T cells undergoing primary and secondary responses to infection in the same host. J. Immunol. 170:4933-4942.

  • Tvinnereim, A.R., Hamilton, S.E., and Harty, J.T. (2002). CD8+ T cell response to secreted and non-secreted antigens delivered by recombinant Listeria monocytogenes during secondary infection. Infect. Immun. 70: 153-162.

  • Hamilton, S.E., and Harty, J.T. (2002). Quantitation of CD8(+) T Cell Expansion, Memory, and Protective Immunity After Immunization with Peptide-Coated Dendritic Cells. J. Immunol. 2002 169(9):4936-4944.

  • Hamilton, S.E., Tvinnereim, A.R., and Harty, J.T. (2001) Listeria monocytogenes Infection Overcomes the Requirement for CD40 Ligand in Exogenous Antigen Presentation to CD8(+) T Cells. J Immunol. 15;167(10):5603-9.

  • Grandea, A. G., III, Golovina, T. N., Hamilton, S. E., Sriram, V., Spies, T., Brutkiewicz, R. R., Harty, J. T., Eisenlohr, L. C., and Kaer, L. V. (2000) Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice. Immunity 13:213-222.

  • Haxhinasto, S.A., and Bishop, G.A. (2004) Synergistic B cell activation by CD40 and the B cell antigen receptor: Role of BCR-mediated kinase activation and TRAF regulation. J. Biol. Chem. 279:2575-2582.

  • Haxhinasto, S.A., Bishop, G.A. (2003) Synergistic B cell activation by CD40 and the B cell antigen receptor: Role of
    BCR-mediated kinase activation and TRAF regulation. J. Biol. Chem., in press.

  • Hostager, B.S., Haxhinasto, S.A., Rowland, S.L., Bishop, G.A. (2003) Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling. J. Biol. Chem. 278:45382-45390.

  • Haxhinasto, S.A. and Bishop, G.A. (2003) A novel interaction between PKD and TRAF molecules regulates BCRCD40 synergy. J. Immunol. 171:4655-62.

  • Bishop, G.A, Haxhinasto, S.A., Stunz, L.L., and Hostager, B.S. (2003) Antigen-specific B lymphocyte activation. Crit. Rev. Immunol. 23:149-197.

  • Haxhinasto, S.A., Hostager, B.S., Bishop, G.A. (2002) Cutting edge: molecular mechanisms of synergy between CD40 and the B cell antigen receptor: role for TNF receptor-associated factor 2 in receptor interaction. J. Immunol. 169(3):1145-1149.

  • Stunz, L.L., Lenert, P., Peckham, D., Yi, A.K., Haxhinasto, S., Chang, M., Krieg, A.M., Ashman, R.F. (2002) Inhibitory oligonucleotides specifically block effects of stimulatory CpG oligonucleotides in B cells. Eur. J. Immunol. 32(5):1212-1222.

  • Hostager, B.S., Hsing, Y., Harms, D.E., and Bishop, G.A. (1996) Different CD40-mediated signaling events require distinct CD40 structural features. J. Immunol. 157:1047-1053.

  • Hsing, Y., Hostager, B.S., and Bishop, G.A. (1997) Characterization of CD40 signaling determinants regulating NF-kB activation in B lymphocytes. J. Immunol. 159:4898-4906.

  • Hsing, Y., and Bishop, G.A. (1999) Requirement for NF-kB activation by a distinct subset of CD40-mediated effector functions in B lymphocytes. J. Immunol. 162:2804-2811.

  • Bishop, G.A., Hsing, Y., Hostager, B.S., Jalukar, S.V., Ramirez, L. and Tomai, M.A. (2000) Molecular mechanisms of B lymphocyte activation by the immune response modifier, R-848. J. Immunol. 165:5552-5557.

  • Kusner, D.J., Hall, C.F. and Jackson, S. (1999) Fcg receptor-mediated activation of phospholipase D regulates macrophage phagocytosis of IgG-opsonized particles. J. Immunol. 162:2266-2274.

  • Kemp, T.J., Kim, J.S., Crist, S.A., and Griffith, T.S. (2003) Induction of necrotic tumor cell death by TRAIL/Apo-2L. Apoptosis. Dec;8(6):587-99.

  • Kemp, T.J., Elzey, B.D., and Griffith, T.S. (2003) Plasmacytoid dendritic cell-derived IFN-alpha induces TNF-related apoptosis-inducing ligand/Apo-2L-mediated antitumor activity by human monocytes following CpG oligodeoxynucleotide stimulation. J Immunol. Jul 1;171(1):212-8.

  • Griffith, T.S., and Kemp, T.J. (2003) The topoisomerase I inhibitor topotecan increases the sensitivity of prostate tumor cells to TRAIL/Apo-2L-induced apoptosis. Cancer Chemother Pharmacol. Sep;52(3):175-84.

  • Kemp, T.J., Moore, J., and Griffith, T.S. (2004) Human B cells express functional TRAIL/Apo-2L after CpG ODN, J. Immunol. July 15;173(2):892-899.

  • Kim, T.S., Butler, N.S. and Perlman, S. (2004) Rapid and robust infiltration of Ly6C hi monocytes into the CNS infected with a neurotropic murine coronavirus. Submitted.

  • Kim, T.S., Templeton, S. and Perlman, S. (2004) Both Complement and Fc gamma Receptors Are Required for Antibody-Mediated Demyelination in Mice infected with a Murine Coronavirus. J. of Immunol. Submitted.

  • Kim, T.S., Perlman, S. (2003) Protection against CTL escape and clinical disease in a murine model of virus persistence. J. Immunol. 171:2006-2013.

  • Ontiveros, E., Kim, T.S. and Perlman, S. (2003) Enhanced Virulence Mediated by the Murine Coronavirus Mouse Hepatitis Virus, strain JHM is associated with a Glycine at Amino Acid 310 of the Spike Glycoprotein . J Virol. 77:10260-10269.

  • Kim, T.S. and Perlman, S. (2003) The role of T cell epitopes in coronavirus infection. In: Experimental Models of Multiple sclerosis. E. Lavi, ed. (in press).

  • Kirsch, J.D., Yi, A.K., Spitz, D.R., Krieg, A.M. (2002) Accumulation of glutathione disulfide mediates NF-kappaB activation during immune stimulation with CpG DNA.Antisense Nucleic Acid Drug Dev. Oct;12(5):327-40.

  • Yi, A-K., Tuetken, R., Redford, T., Waldschmidt, M., Kirsch, J., and Krieg, A.M. (1998) CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species, J. Immunol. 160:4755-4761.

  • Latinis, K., and Koretzky, G. (1996) Fas Ligation induces apoptosis and Jun Kinase activation independently of CD45 and Lck in human T cells. Blood 87:871-875.

  • Latinis, K.M., Norian, L.A., Eliason, S.L., and Koretzky, G.A. (1997) Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells. J. Biol. Chem. 272:31427-31434.

  • Latinis, K.M., Carr, L.L., Peterson, E.J., Norian, L.A., Eliason, S.L., and Koretzky, G.A. (1997) Regulation of CD95 (Fas) ligand expression by TCR-mediated signaling events. J. Immunol. 158:4602-4611.

  • Peterson, E.J., Latinis, K.M. and Koretzky, G.A. (1998) Molecular characterization of a CD95 signaling mutant. Arthritis Rheum. 41:1047-1053.

  • Faris, M., Kokot, N., Latinis, K., Kasibhatla, S., Green, D.R., Koretzky, G.A. and Nel, A. (1998) The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas ligand expression. J. Immunol. 160:134-144.

  • Faris, M., Latinis, K.M., Kempiak, S.J., Koretzky, G.A. and Nel, A. (1998) Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter. Mol. Cell. Biol. 18:5414-5424.

  • Weiner, G.J., Liu, H., Wooldridge, J.E., Dahle, C.E. and Krieg, A.M. (1997) Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization. PNAS. 94:10833-10837.

  • Liu, H., Newbrough, S.E., Bhatia, S., Dahle, C.E., Krieg, A.M. and Weiner, G.J. (1998) Immunostimulatory CpG oligodeoxynucleotides enhance the immune response to vaccine strategies involving GM-CSF. Blood 92:3730-3736.

  • Malik, Z.A., Thompson, C.R., Hashimi, S., Porter, B., Iyer, S.S., Kusner, D.J. (2003) Cutting Edge: Mycobacterium tuberculosis Blocks Ca(2+) Signaling and Phagosome Maturation in Human Macrophages Via Specific Inhibition of Sphingosine Kinase. J Immunol. Mar 15;170(6):2811-5.

  • Malik, Z.A., Denning, G., and Kusner, D.J. (2000) Inhibition of Ca2+ signaling by mycobacterium tuberculosis is associated with reduced phagosome-lysosome fusion and increased survival within human macrophages. J. Exp. Med. 191:287-302.

  • Myung, P.S., Clements, J.L., White, D.W., Malik, Z.A., Cowdery, J.S., Allen, L.H., Harty, J.T., Kusner, D.J., and Koretzky, G.A. (2000) In vitro and in vivo macrophage function can occur independently of SLP-76. Int. Immunol. 12:887-897.

  • Malik, Z.A., Iyer, S.S., and Kusner, D.J. (2001) Mycobacterium tuberculosis phagosomes exhibit altered calmodulin-dependent signal transduction. Contribution to inhibition of phagosome-lysosome fusion and intracellular survival in human macrophages. J. Immunol. 166:3392-3401.

  • Hovis, R.R., Donovan, J.A., Musci, M.A., Motto, D.G., Goldman, F.D., Ross, S.E., and Koretzky, G.A. (1993) Rescue of signaling by a chimeric protein containing the cytoplasmic domain of CD45. Science 260:544-546.

  • Motto, D.G., Musci, M.A., and Koretzky, G.A. (1994) Surface expression of a heterologous phosphatase complements CD45 deficiency in a T cell clone. J. Exp. Med. 180:1359-66.

  • Motto, D.G., Musci, M.A., Ross, S.E., and Koretzky, G.A. (1996) Tyrosine phosphorylation of Grb2-associated proteins correlates with phospholipase Cg1 activation in T cells. Mol. Cell. Biol. 16:2823-2829.

  • Musci, M. A., Latinis, K. M., and Koretzky, G. A. (1997) Signaling events in T lymphocytes leading to cellular activation or programmed cell death. Clin. Immunol. Immunopathol. 83:205-222.

  • Musci, M.A., Beaves, S.L., Ross, S.E., Yi, T., and Koretzky, G.A. (1997) Surface expression of hemopoietic cell phosphatases fails to complement CD45 deficiency and inhibits TCR-mediated signal transduction in a Jurkat T cell clone. J. Immunol. 158:1565-71.

  • Musci, M.A., Motto, D.G., Ross, S.E., Fang, N. and Koretzky, G.A. (1997) Three domains of SLP-76 are required for its optimal function in a T cell line. J. Immunol. 159:1639-1647.

  • Musci, M.A., Hendricks-Taylor, L.R., Motto, David G., Paskind, M., Kamens, J., Turck, C.W., and Koretzky, G.A. (1997) Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases. J. Biol. Chem. 272:11674-11677.

  • Nanra, J.S., Takahashi, K., Tygrett, L.T., Wiechert, S., Rennert, P.D. and Waldschmidt, T.J. (2003) Marginal zone maintenance and optimal TI-2 antibody responses require cooperation between LTab and TNFa.
    (submitted).

  • Nanra, J.S., Takahashi, K., Tygrett, L.T., Wiechert, S.C., Rennert, P.D., and Waldschmidt, T.J. (2004) Marginal zone maintenance and optimal TI-2 antibody responses require cooperation between LT alpha beta and TNF alpha. Submitted.

  • Norian, L.A., Latinis, K.M., Eliason, S.L., Lyson, K., Yang, C., Ratliff, T., and Koretzky, G.A. (2000) The regulation of CD95 (Fas) ligand expression in primary T cells: induction of promoter activation in CD95LP-Luc transgenic mice.
    J. Immunol.164(9):4471-4480.

  • Norian, L.A., and Koretzky, G.A. (2000) Intracellular adapter molecules. Semin. Immunol. 12:43-54. Review.

  • Norian, L.A., Latinis, K.M., and Koretzky, G.A. (1998) A newly identified response element in the CD95 (Fas) ligand promoter contributes to optimal inducibility in activated T lymphocytes. J. Immunol. 161:1078-1082.

  • Cowdery, J.S., Boerth, N.J., Norian, L.A., Myung, P.S., and Koretzky, G.A. (1999) Differential regulation of the IL-12 p40 promoter and of p40 secretion by CpG DNA and lipopolysaccharide. J. Immunol. 162:6770-6775.

  • Norian, L.A., and Koretzky, G.A. (1999) TCR-induced signaling for cytotoxicity: The regulation of CD95L (Fas Ligand) expression in activated T lymphocytes, In "Cytotoxic Cells: Basic Mechanisms and Medical Applications", Editors: Ditovsky, M.V. And Henkart, P.A., Publisher, Lippincott-Raven, in press.
  • Ontiveros, E., Kim, T.S., Gallagher, T.M., Perlman, S. (2003) Enhanced virulence mediated by the murine coronavirus, mouse hepatitis virus strain JHM, is associated with a glycine at residue 310 of the spike glycoprotein. J. Virol. 77:10260-10269.

  • Ontiveros, E., Kuo, L., Masters, P.S., and Perlman, S. (2001) Inactivation of Expression of Gene 4 of Mouse Hepatitis Virus Strain JHM Does Not Affect Virulence in the Murine CNS. Virology. 289(2): 230-238.

  • Ontiveros, E., Kuo, L., Masters, P., and Perlman, S. (2001) Analysis of nonessential gene function in recombinant MHV-JHM. Gene 4 knockout recombinant virus. Adv. Exp. Med. Biol. 494:83-9.

  • Badovinac, V. P., Porter, B.B. and Harty, J.T. (2004) CD8+ T cell contraction is controlled by early inflammation Published online: 11 July 2004 | doi:10.1038/ni1098.

  • Badovinac, V.P., Porter, B.B., Harty, J.T. (2002) Programmed contraction of CD8(+) T cells after infection. Nat. Immunol. 7:619-26.

  • Li, Y.-Y., Smith, K.D., Shi, Y., and Lutz, C.T. (1996) Alloreactive anti-HLA-B7 cytolytic T cell clones use restricted T cell receptor genes. Transplantation 62:954-961.

  • Shi, Y., Smith, K.D., Kurilla, M.G., and Lutz, C.T. (1997) Cytotoxic CD8+ T cells recognize EBV antigen but poorly kill autologous EBV-infected B lymphoblasts. J. Immunol. 159:1844-1852.

  • Shi, Y., K.D. Smith, and Lutz, C.T. (1998) TAP-independent MHC class I peptide antigen presentation to alloreactive CTL is enhanced by target cell incubation at subphysiologic temperatures. J. Immunol 160:4305-4312.

  • Shi, Y., and Lutz, C.T. (2002) Interferon-g control of EBV-transformed B cells. A role for CD8+ T cells that poorly kill EBV-infected cells. Viral Immunol. 15:213-225.

  • Shinall, S.M., Wolniak, K.L., Cozine, C., Dandekar, A.A., Perlman, S., and Waldschmidt, T.J. (2004) Antigen- and Stain- Independent Characteristics of the Primary Germinal Center Reaction in Mice. Submitted.

  • Shinall, S.M., Gonzalez-Fernandez, M., Noelle, R.J., Waldschmidt, T.J. (2000) Identification of murine germinal center B cell subsets defined by the expression of surface isotypes and differentiation antigens. J. Immunol. 164:5729-5738.

  • Takahashi, K., Kozono, Y., Waldschmidt, T., Berthiaume, D., Quigg, R.J., Baron, A., and Holers, V.M. (1997) Mouse complement receptors Type 1 (CR1, CD35) and 2 (CR2, CD21): Expression on normal B cell subpopulations and decreased levels during the development of autoimmunity in MRL/1pr mice. J. Immunol. 159:1557-1569.

  • Griffith, T.S., Kawakita, M., Tian, J., Ritchey, J., Tartaglia, J., Sehgal, I., Thompson, T.C., Zhao, W., Ratliff, T.L. (2001) Inhibition of murine prostate tumor growth and activation of immunoregulatory cells with recombinant canarypox viruses. J. Natl. Cancer Inst. 93:998-1007.
  • Elzey, B.D., Tian, J., Jensen, R.J., Swanson, A.K., Lees, J.R., Lentz, S.R., Stein, C.S., Nieswandt, B., Wang, Y., Davidson, B.L., Ratliff, T.L. Platelet-mediated modulation of adaptive immunity. A communication link between
    innate and adaptive immune compartments.
    Immunity. 2003 1:9-19.

  • VanOosten, R.L., Moore, J.M., Ludwig, A., and Griffith, T.S. (2004) Depsipeptide (FR901228) enhances the cytotoxic activity of TRAIL by increasing the levels of TRAIL receptor within membrane lipid rafts. Submitted.

  • White, D.W., Wilson, R.L., and Harty, J.T. (1996) CD8+ Tcells in intracellular bacterial infections in mice. Res. Immunol. 147:519-524.

  • White, D. W. and Harty, J.T. (1998) Perforin-deficient CD8+ T cells provide immunity to Listeria monocytogenes by a mechanism which is independent of CD95 and IFNg but requires TNFa. J. Immunol. 160:898-905.

  • White, D. W. , MacNeil, A., Busch, D.H., Pilip, I.M. , Pamer, E.G. and Harty, J.T. (1999) Perforin-deficient CD8+ T cells in vivo: priming and antigen specific immunity against Listieria monocytogenes. J. Immunol. 162:980-988.

  • White, D. W., Badovinac, V.P., Fan, X. and Harty, J.T. (2000) Adaptive immunity against Listeria monocytogenes in the absence of type I tumor necrosis factor receptor p55. Infect. Immun. 68: 4470-4476.

  • White, D. W., Badovinac, V.P., Kollias, G. and Harty, J.T. (2000) Cutting Edge: Antilisterial activity of CD8+ T cell derived From TNF-deficient and TNF/perforin double-deficient mice. J. Immunol. 165:5-9.

  • Harty, J.T., Tvinnereim, A.R., and White, D.W.(2000) CD8+ T cell effector mechanisms in resistance to infection. Annu. Rev. Immunol. 18:275-308. Review.

  • Wilson, R.L., White, D.W., and Harty, J.T. (2000) Transient expression of bacterial gene fragments in eukaryotic cells:
    implications for CD8(+) T cell epitope analysis. J. Immunol. Methods. 234:137-47.


  • Harty, J.T., and White, D. (1999) A knockout approach to understanding CD8+ cell effector mechanisms in adaptive
    immunity to Listeria monocytogenes. Immunobiology. 201:196-204. Review.

  • Wolniak, K.L., Shinall, S.M., and Waldschmidt, T.J. (2004) The primary germinal center response. Crit. Rev. Immunol. 24:39-66.

  • Wolniak, K.L., Noelle, R.J., Shlomchik, M.J., and Waldschmidt, T.J. (2004) Flow cytometric analysis of the primary (4-hydroxy-3-nitrophenyl)acetyl specific B cell response in mice. Characterization of antigen-binding B220+ germinal center and B220- splenic populations. Submitted.

  • Zhao, L., Shey, M., Farnsworth, M., Dailey, M.O. (2001) Regulation of membrane metalloproteolytic cleavage of L-selectin (CD62l) by the epidermal growth factor domain. J. Biol. Chem. Aug 17;276(33):30631-40.

  • Zhao, L., Edgar, J., and Dailey, M.O. (2001) Characterization of the rapid proteolytic shedding of murine L-selectin. Dev. Immunol. 8(3-4):267-77.