Warren G. Darling, Ph.D.
Professor

Doctoral Degree: Physiology
Institution: University of Western Ontario (1985)

Office: 530 Field House
Office Phone: (319) 335-9514
e-mail:  warren-darling@uiowa.edu

Research Interests:
Our research focuses on control of upper limb movements and recovery of hand/digit fine motor function after brain injury.  The overall research goals are to understand:  (1) mechanisms underlying recovery of fine hand/digit movement control after brain injury, (2) effects of exercise on fine hand/digit movement control and cognitive function in individuals with Parkinson’s Disease and (3) fine hand/digit movement control in elderly individuals.  (4) how the brain processes visual, vestibular and proprioceptive information to specify location, orientation and motion of objects and the upper limb in young and elderly subjects.

Recent Publications:

McNeal, D.W., Darling, W.G., Ge, J., Stilwell-Morecraft, K.S., Solon, K., Hynes, S.M., Pizimenti, M.A., Rotella, D.L., Vanadurongvan, T., Morecraft, R.J. (in press) Selective long-term reorganization of the corticospinal project from the supplementary motor cortex following recovery from lateral motor cortex injury.  Journal of Comparative Neurology (pdf)

Darling, W.G., Pizzimenti, M.A., Rotella, D.L., Peterson, C.R., Hynes, S.M., Ge, J., Solon, K., McNeal, D.W., Stilwell-Morecraft, K.S., Morecraft, R.J. (in press) Volumetric effects of motor cortex injury on recovery of dexterous movements.  Experimental Neurology pdf 

Darling, W.G., Viaene, A.N., Peterson, C.R., Schmiedeler, J.P. (2008) Perception of hand motion direction uses a gravitational reference.  Experimental Brain Research 186:237-248. pdf

Simmering, V.R., Peterson, C., Darling, W.G., Spencer, J.P. (2008) Location of memory biases reveal the challenges of coordinating visual and kinesthetic reference frames.  Experimental Brain Research 184:165-178.** pdf

Pizzimenti MA, Darling WG, Rotella DL, Herrick JL, Ge J, McNeal DW, Stilwell-Morecraft KS, Morecraft RJ (2007) Measurement of Reaching Kinematics and Prehensile Dexterity before and after lesion of cortical arm motor areas in Non-Human Primates. Journal of Neurophysiology 98:1015-1029* pdf

Darling, W.G., Bartelt, R.B., Pizzimenti, M.A., Rizzo, Matthew (in press) Spatial perception errors do not predict pointing errors by individuals with brain lesions.  Journal of Clinical and Experimental Neuropsychology *

Darling, W.G., Seitz, R.J., Peltier, S., Tellman, L., Butler, A.J. (2007) Visual cortex activation in kinesthetic guidance of reaching.  Experimental Brain Research 179:607-619 ^* pdf

Ethier, C., Brizzi, L., Darling, W.G., Capaday, C. (2006) Linear Summation of Cat Motor Cortex Outputs.  Journal of Neurscience 26:5574-5581 (correction published in J. Neurosci 26:6115) ** pdf

Darling, W.G., Wolf, S.L., Butler, A.J. (2006) Variability of Motor Evoked Potentials Induced by Transcranial Magnetic Stimulation Depends on Muscle Activation.   Experimental Brain Research 174:376-385. * pdf

Darling, W.G., Peterson, C.R., Herrick, J.L., McNeal, D.W., Stilwell-Morecraft, K.S., Morecraft, R.J. (2006) Measurement of Coordination of Object Manipulation in Non-human Primates.  Journal of Neuroscience Methods 154:38-44 *  pdf

Darling, W.G. and Bartelt, R.  (2005) The visual perception coordinate system uses axes defined by earth, trunk and vision.  Perception 34:17-30 * pdf

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