Research Projects

The multidisciplinary connections of the Research Projects are shown in Figure II. Overall, the exchange of expertise, samples and data among the six Research Projects of the isbrp as well as the thematic connections will help us to answer several questions, such as: Where are sources of airborne PCBs? What are the levels of human exposures to these types of PCBs? What are the potential roles of metabolism in biological responses to semi-volatile PCBs? What are the human health effects? How can we remediate PCB contaminated sites?

Project 1: PCBs: Metabolism, Genotoxicity and Gene Expression in Vivo
Larry Robertson, Gabriele Ludewig, Garry Buettner, Howard Glauert

Project 2: Oxidative Stress and PCB Exposure in Mammalian Cells
Prabhat Goswami, Douglas Spitz, Frederick Domann

Project 3: PCBs and Hydroxysteroid (Alcohol) SuIfotransferases
Michael Duffel, Larry Robertson, Hans-Joachim Lehmler

Project 4: Atmospheric Sources of PCB Congeners
Keri Hornbuckle, Greg Carmichael, Peter Thorne

Project 5: Phytoremediation to Degrade Airborne PCB Congeners from Soil and Groundwater Sources
Jerry Schnoor, Timothy Mattes, Benoit Van Aken, Hans Joachim-Lehmler

Project 6: AESOP Study: Characterization of Exposures of Urban and Rural Cohorts to Airborne PCBs
Peter Thorne, Keri Hornbuckle, Kai Wang, David Osterberg, Fredric Gerr

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