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Why Cell Biology Cannot be Reduced to Physics

Alice B. Fulton, Professor Department of Biochemistry
and Director, Honors Program, The University of Iowa

Alice B. Fulton joined the faculty of the Department of Biochemistry at the University of Iowa in 1981. In 1977 she earned her Ph.D. in cell biology from Brown University and from 1977-81 completed two postdoctoral fellowships at Brandeis University and M.I.T.. She has served as director of the University of Iowa Honors Program since 1998 and as director of the Women in Science and Engineering program from 1995-1998. Fulton's numerous publications include articles in scientific journals, such as Journal of Cell Biology, Molecular Genetics and Metabolism, Pediatric Research, Proceedings of the National Academy of Science (PNAS), and Journal of Cell Science, as well as book chapters, review articles, and a book, The Cytoskeleton: Cellular Architecture and Choreography. She is a 1995 Fellow of the American Association for the Advancement of Science.

Paper Description: The paper explores the claim that cell biology is in many important respects not reducible into the terms of physics, not for practical limitations but in principle. It cannot be reduced to physics because for many terms that it uses there is no single nor any collection of atoms or molecules that exactly map to that which the term from cell biology describes. The fuzzy and historical properties of cells are described as support for this claim and a gedanken experiment applies them to cells.

I have avoided the "emergent properties" debate for several reasons. One is that one possible audience for this paper would be scientists, most of who are unfamiliar with or skeptical about emergent properties. A second reason is that I myself have trouble holding in mind an understanding of emergent properties that would let me apply it to this situation.

I would also appreciate suggestions about an audience for this paper. I wrote it to capture the realization that the gedanken experiment described here had implications for the reducibility to physics. It might be appropriate as a "thought piece" in journals such as Nature, Cell or the Journal of Cell Science. However there may be a different audience for which it is better suited. —AF


 

[Thursday, November 14, 2002; 7:30-9:30 PM; 204 Jefferson Building]

 

 

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