The Salem Laboratory
of Advanced Drug and Gene Delivery
The Salem Laboratory
of Advanced Drug and Gene Delivery
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| Listed below is notices, reminders, current meetings, times and dates Notices and Reminders:Please remember to bring all packing sheets, invoices and receipts to S228 for consolidation. Meetings:Group meetings to be held weekly on Monday at 12.30pm - 1.30pm. Presenter should e-mail group 2 days before meeting to confirm. Presenter must present research progress to date. If you are supplementing research progress with a paper presentation, then please forward a PDF to the rest of the group prior to meeting.
Current tentative schedule for presentations:
August 10th: Aiman Abbas August 17th: NaJung Kim August 24th: Dahai Jiang August 31st: Jessica Melanko September 14th: Yogita Krishnamachari September 21st: Sean Geary September 28th: Caitlin Lemke October 5th: Donna Santillan (Hunter) October 12th: Vijaya Joshi October 19th: Sheetal D'Mello
Salem-Lubaroff Prostate Cancer Vaccine Project Meetings: Once every other Monday 2-3pm
Salem-Weiner Melanoma Vaccine Project Meetings: Once every other Monday 11am-12pm
Salem-Sandler Neuroblastoma Vaccine Conference Calls: Once every other week (from Oct 2009)
Salem-Hunter Group B Streptococci Vaccine Project Meetings: Once every other week (from Sept 2009)
Salem-Behlke siRNA Delivery Project Meetings: Arranged as new data justifies.
Supervisory Meetings: Monthly meetings during the current session will be held on the first Wednesday of every month. The times for the meetings will be:
12.30-1.00 Vijaya 1.00-1.30 Sheetal 1.30-2.00 NaJung 2.00-2.30 Caitlin 2.30-3.00 Sean 3.00-3.30 Yogita 3.30-4.00 Dahai 4.00-4.30 Jessica
4.30-5.00 Aiman
Additional Group Presentations/Schedule: April 7th 2005: Poster presentation by T. Terry at the College of Engineering Open House April 7th 2005: Poster presentation by N. Baman at the College of Engineering Open House April 26th 2005: Cancer Immunology presentation by A. Salem at Cancer Center Forum June 10th 2005: Cancer Immunology presentation by A. Salem at UI/Mayo Clinic SPORE meeting August 28th 2005: Three presentations by A. Salem, J. Sinclair and N. Baman at 230th national meeting & exposition of the American Chemical Society in Washington, DC October 3rd 2005: Immunotherapeutic Vaccine Development using Biodegradable Microparticles that Co-entrap CpG ODN Adjuvants and Antigens Presentation by A. Salem at CpG symposium October 14th 2005: Vaccine development against Cancers presentation by A.Salem at UI/Mayo Clinic Lymphoma SPORE meeting October 30th 2005: Presentation by T. Terry at American Institute of Chemical Engineers 2005 Annual Conference, Cincinnati, OH December 1st 2005: "The pharmaceutical applications of nanotechnology" by A. Salem at Department of Chemistry, College of Liberal Arts and Sciences. February 2nd 2006: Argonne National Laboratory, Illinois Chemical Engineering Division Seminar: "Biodegradable Polymers with Generic Functional Attachment" by A. Salem, University of Iowa. 10:30 a.m., Building 205, Y-Wing Auditorium. March 25th 2006. Immunostimulatory antigen loaded microparticles. NK Baman, AD Sandler, GJ Weiner, X Zhang, X Zhu, CE Dahle, AK Salem. James F. Jakobsen Conference 2006 April 1st 2006. Geometric control over cell binding on degradable substrates. D Sharma, J Mowers, J Sinclair, AK Salem. Spring Undergraduate Research Forum 2006. April 12th 2006: Ternary particle vaccine for effective delivery to the pulmonary system. TL Terry, VGJ Rodgers, AK Salem, Annual Conference of the National Organization for Professional Advancement of Black Chemists and Chemical Engineers, Los Angeles. April 13th 2006: "Nanoparticles that provide cancer protection" presentation by A. Salem at Department of Chemistry, College of Liberal Arts and Sciences. May 31st - June 4th 2006: Immunostimulatory antigen loaded microparticles as cancer vaccines. AK Salem, AD Sandler, GJ Weiner, X Zhang, NK Baman, X Zhu, CE Dahle. American Society of Gene Therapy 9th Annual Meeting, Baltimore MD. June 8th-June 10th 2006: A. Abbas, J. Intra and TL Terry present at Pharmaceutics Graduate Student Research Meeting 2006, University of Minnesota. August 2nd-4th 2006: AK Salem at Department of Defense (DoD): Congressionally Directed Medical Research Programs (CDMRP) Breast Cancer Clinical and Experimental Therapeutics Grant Review Panel Meeting September 10th - 14th, 2006: A.K. Salem presents 1) Preparation and Characterization of Hybrid Poly(lactic-co-glycolic acid)/ Polyethylenimine Particles as Non-Viral Gene Delivery Systems. 2) Utilizing microfluidics for spatial control over cell attachment on biodegradable polymers and 3) Biodegradable Microparticle Delivery of Antigens and Adjuvants Stimulate Potent Anti-Tumor Antigen-Specific Immune Responses. American Chemical Society Meeting & Exposition San Francisco, CA USA September 28th 2006: Co-Delivery of Antigens and Adjuvants from Biodegradable Particles Stimulate Potent Antigen-Specific Anti-Tumor Immune Responses. AK Salem at Department of Chemical and Biological Engineering, Iowa State University. 11:00 a.m., in Room 171 Durham. October 23rd 2006: 4 Poster presentations at Center for Biocatalysis and Bioprocessing Conference. J Intra, X Zhang, A Abbas, AK Salem October 29th - November 2nd, 2006: Immunostimulatory antigen loaded microparticles as cancer vaccines. X Zhang, CE Dahle, NK Baman, X Zhu, AD Sandler, GJ Weiner, AK Salem. 2006 AAPS Annual Meeting and Exposition, San Antonio, TX October 29th - November 2nd, 2006: Preparation and Characterization of Hybrid Poly(lactic-co-glycolic acid)/ Polyethylenimine Particles as Non-Viral Gene Delivery Systems . J Intra, X Zhang, AK Salem. 2006 AAPS Annual Meeting and Exposition, San Antonio, TX November 12th-17th 2006: Ternary particles for gene delivery. T.L Terry, V.G.J. Rodgers, A.K. Salem, American Institute of Chemical Engineers 2006 Annual Conference, San Francisco, California March 1st 2007: Innovative strategies for co-delivery of CpG oligonucleotides and antigens. A.K. Salem at University of Illinois at Chicago, College of Pharmacy, Dept. of Biopharmaceutical Sciences. March 9th 2007: Tissue Engineering and Gene Delivery. A.K. Salem at College of Pharmacy, Drake University March 18th-20th 2007: A.K. Salem at Department of Defense (DoD): Congressionally Directed Medical Research Programs (CDMRP) Breast Cancer Clinical and Experimental Therapeutics Grant Review Panel Meeting August 15th-17th 2007: A.K Salem at Department of Defense (DoD): Congressionally Directed Medical Research Programs (CDMRP) Breast Cancer Clinical and Experimental Therapeutics Grant Review Panel Meeting September 27th 2007: Nanoparticles that immunotherapeutically prevent and treat cancer. A.K. Salem at the Nanoscience and Nanotechnology Institute at UI Fall 2007 Symposium, University of Iowa. 2.00 pm, 2117 MERF. A.K. Salem part of panel on discussion of NanoHealth: Nanoscience and Nanotechnology in Clinical and Translational Medicine at 4.00pm. October 16th 2007: A.K. Salem gives the Inaugural Merck/AAAS Undergraduate Science Research Program Lecture at Augustana College, Illinois October 18th 2007: A.K. Salem is invited Participant on the Graduate College Open House Panel “Preparing for Graduate Education – Building a Competitive Application. University of Iowa. October 24th 2007: Polymeric particles that augment CpG oligonucleotide mediated immune responses. A.K. Salem. UI/Mayo Clinic Lymphoma SPORE scientific retreat. November 2nd-3rd 2007: A.K. Salem at Fifth International Nanomedicine And Drug Delivery Symposium, Boston, MA. Multi-Component Nanorods for Genetic Vaccination Applications November 11th - 15th 2007: Conjugation of Polyamidoamine Dendrimers on Biodegradable Microparticles for Non-Viral Gene Delivery. J. Intra, X.Q. Zhang, A.K. Salem. 2007 AAPS Annual Meeting and Exposition, San Diego, CA. November 11th - 15th 2007: A Novel Biotinylated Chitosan for Gene Delivery and Tissue Engineering Applications. A.O. Abbas, M.D. Donovan, A.K. Salem. 2007 AAPS Annual Meeting and Exposition, San Diego, CA. January 10th-11th 2008: A.K. Salem at Susan G. Komen Breast Cancer Grant Review Panel. February 13th 2008: A.K. Salem at the Immunology Graduate Program, University of Iowa on "Advanced Drug Delivery Strategies for Enhancing Immunotherapeutic Efficacy of Cancer Vaccines" March 28th 2008: A.K. Salem at the Prostate Cancer Research Program, Department of Urology, College of Medicine, University of Iowa on "Nanoparticles that Augment Prostate Cancer Vaccines" June 26th-28th 2008: J.B. Graham, E. Donahey, D.M. Lubaroff, A.K. Salem. Co-delivery of cationic polymers and adenovirus enhance tumor protection in a murine model of prostate cancer. Pharmaceutics Graduate Student Research Meeting 2008, University of Michigan. July 9th 2008: A.K. Salem at the Department of Chemistry, College of liberal Arts and Sciences, University of Iowa for NSF REU program. Nanotechnology in Drug Delivery July 20th- 22nd 2008: A.K Salem at Department of Defense (DoD): Congressionally Directed Medical Research Programs (CDMRP) Breast Cancer Clinical and Experimental Therapeutics Grant Review Panel Meeting September 2nd 2008: A.K. Salem at the Division of Medicinal Chemistry and Natural Products, College of Pharmacy, University of Iowa. Innovative strategies for co-delivery of CpG oligonucleotides and antigens. September 11th-12th, 2008: A.K. Salem. Immunostimulatory antigen loaded microparticles as cancer vaccines. Cancer Immunology and Immunotherapy: Realizing the Promise, National Institutes of Health, Bethesda, MD October 16th 2008: A.K. Salem. Innovative strategies for co-delivery of CpG oligonucleotides and antigens.Department of Biomedical Engineering, College of Engineering, University of Iowa. November 16th-21st 2008: J.B. Graham, E. Donahey, D.M. Lubaroff, A.K. Salem. Co-delivery of cationic polymers and adenovirus enhance tumor protection in a murine model of prostate cancer. American Institute of Chemical Engineers 2008 Annual Conference, Philadelphia, PA November 16th-20th 2008: D. Jiang, N. Kim, A.K. Salem. Polyethylenimine (PEI)-Polyethylene glycol (PEG)-Mannose and Chitosan-PEG-Mannose Tri- Component Vehicles for siRNA Delivery. 2008 AAPS Annual Meeting and Exposition, Georgia World Congress Center, Atlanta, GA November 16th-20th 2008: J. Intra, J.M Glasgow, H. Q. Mai, A.K. Salem. Pulsatile release of biomolecules from polydimethylsiloxane (PDMS) chips with hydrolytically degradable seals. 2008 AAPS Annual Meeting and Exposition, Georgia World Congress Center, Atlanta, GA November 16th-20th 2008: J. Intra, A.K. Salem. Characterization of the transgene expression generated by branched and linear polyethylenimine-plasmid DNA nanoparticles in vitro and after intraperitoneal injection in vivo. 2008 AAPS Annual Meeting and Exposition, Georgia World Congress Center, Atlanta, GA November 16th-20th 2008: Y. Krishnamachari and A.K. Salem. Self-assembly of a cell-microparticle hybrid as a multifunctional drug delivery vehicle. Proceedings of the American Association for Pharmaceutical Scientists. 2008 AAPS Annual Meeting and Exposition, Georgia World Congress Center, Atlanta, GA November 16th-20th 2008: Y. Krishnamachari and A.K. Salem. Receptor mediated enhancement of the transfection efficiency generated by chitosan-plasmid DNA nanoparticles in vitro. 2008 AAPS Annual Meeting and Exposition, Georgia World Congress Center, Atlanta, GA December 10th 2008: A.K. Salem at the Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa. Innovative strategies for co-delivery of CpG oligonucleotides and antigens. March 6th 2009: A.K. Salem at the Interdisciplinary graduate program in Human Toxicology, Department of Public Health, College of Public Health, University of Iowa. Innovative strategies for co-delivery of antigens and immunostimulatory adjuvants. April 2009: N. Kim, D. Jiang, A.K. Salem. Polyethylenimine (PEI)-Polyethylene glycol (PEG)-Mannose and Chitosan-PEG-Mannose Tri- Component Vehicles for siRNA Delivery. Society for Biomaterials Annual Meeting. May 14th 2009: A.K. Salem is keynote speaker at the Annual American Cancer Society Research and Recognition Dinner. May 29th 2009: A.K. Salem. Innovative strategies for co-delivering antigens and immunostimulatory oligonucleotides. American Society of Gene Therapy 12th Annual Meeting, San Diego CA. June 19th 2009: American Cancer Society Relay for Life Johnson County (Lap the Track with ACS Researchers) September 18th 2009: A.K. Salem. Utilization of clicker technology in lectures in the PharmD program. 1st UI Clicker User Conference, University of Iowa November 8th-12th 2009: Y. Krishnamachari, C. Lemke, C.E. Dahle, G.J. Weiner, A.K. Salem. PLGA microparticles that co-deliver antigen and toll like receptor ligand adjuvants for applications in cancer immunotherapy. 2009 AAPS Annual Meeting and Exposition, Los Angeles Convention Center, Los Angeles, CA, USA. November 8th-12th 2009: D. Jiang, A.K. Salem. A novel dextran-polyethylenimine conjugate polymer for polynucleotides delivery. 2009 AAPS Annual Meeting and Exposition, Los Angeles Convention Center, Los Angeles, CA, USA. November 8th-12th 2009: A. O. Abbas, M. D. Donovan, A. K. Salem. Chitosan-Dextran Sulfate as Vaccine Delivery Systems. 2009 AAPS Annual Meeting and Exposition, Los Angeles Convention Center, Los Angeles, CA, USA. November 8th-12th 2009: A. O. Abbas, M. D. Donovan, A. K. Salem. Biotinylated Chitosan Applications in Enzyme Immobilization. 2009 AAPS Annual Meeting and Exposition, Los Angeles Convention Center, Los Angeles, CA, USA. November 11th to November 13th 2009: A.K. Salem. Innovative strategies for co-delivering tumor specific antigens and immunostimulatory oligonucleotides. American Cancer Society 2009 Professors Meeting. Naples, Florida, USA.
Lab cleaning day
Schedule for cell culture room cleaning - click here (excel file) Schedule for purchasing at biochem stores - click here (excel file)
Every week on Friday at 5pm Caitlin/Sean- Cell culture room, Yogita/Dahai/NaJung - Main Lab Aiman - Microscope room and equipment maintenance Jessica/Yogita - Stocks and ordering Jessica- liquid nitrogen in cryochamber
Key External Presentations for Group to attend: 20th September 2004: Pharmaceutics Seminar, Tony Mikos, Ph.D.; J.W. Cox, Professor, Department of Bioengineering, Rice University, "Drug and Cell Delivery from Injectable, Biodegradable Polymeric Scaffolds for Tissue Engineering", 4:00-5:00 pm in S538. 4th October 2004: Pharmaceutics Seminar, Dexi Liu, Ph.D.; Associate Professor, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 4:00-5:00 pm, S538 Phar, 22nd November 2004: Pharmaceutics Seminar, Ronald T. Borchardt, Ph.D.; Solon E. Summerfield Distinguished Professor, Department of Pharmaceutical Chemistry, School of Pharmacy, University of Kansas, 4:00-5:00, S538 Phar 13th December 2004: Pharmaceutics Seminar, William J. Jusko, Ph.D.; Professor and Chair, Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, "Pharmacodynamics and Pharmacogenomics of Corticosteroids", 4:00-5:00 pm, S538 Phar 18th January 2005: David J. Mooney, Gordon McKay Professor of Bioengineering, Harvard University presents a seminar entitled Designing materials to regulate bone regeneration on Tuesday at 12:00 Noon, January 18, 2005 in the Galagan Auditorium B, LeRoy Larson Classroom of the Dental Science Building. February 14 2005: Ned B. Bowden, Ph.D.; Assistant Professor, Department of Chemistry, The University of Iowa, 4:00-5:00 pm, S538 Phar February 15 2005: High throughput Salt Screening and Selection During Lead Optimization: Optimizating Physical Properties of Drug Candidates Gregory A. Stephenson, Ph.D.; Research Advisor; Eli Lilly and Company, 4:00-5:00 pm, S538 Phar March 21st 2005: Pharmacodynamics of Ciprofloxacin Resistance in Staphylococcus aureus Patrick J. McNamara, Ph.D.; Professor and Chair, Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 4:00-5:00 pm, S538 Phar April 25 2005: The Pharmaceutical Enterprise Under the Microscope: It is Time to Innovate and Integrate. Vincent Lee, Ph.D., D.Sc.; Associate Director, Office of Pharmaceutical Science, Center for Drug Evaluation and Research, Food and Drug Administration, 4:00-5:00 pm, S538 Phar May 9 2005: Development of Nanocrystalline Zeolite Structures for Potential Applications in Gene Delivery Sarah Larsen, Ph.D.; Associate Professor, Department of Chemistry, The University of Iowa, 4:00-5:00 pm, S538 Phar September 12 2005: Modern Biopharmaceutics: Membrane Transport and Activation of Prodrugs. Gordon Amidon, Ph.D., University of Michigan, 4:00-5:00 pm, S538 Phar October 3 2005: "Emerging Issues Affecting Pulmonary Drug Disposition and Regulation" Peter Byron, Ph.D., Virginia Commonweath University, 4:00-5:00 pm, S538 Phar January 20th 2006: "From Three Dimensions to Two: Chemistry and Biology at Interfaces" Milan Mrksich, Ph.D., University of Chicago 3:30 in C107 PBB.February 6th 2006: Polymer nanostructure formation in liquid crystals, C Allan Guymon, Ph.D., University of Iowa, 4-5pm, S538 Phar March 6th 2006: Developability: Applying Pharmaceutical Science in Lead Optimization, David S. Collins, Ph.D., Eli Lilly and Company. 4-5pm, S538 Phar September 18th 2006: Samuel Yalkowsky, Ph.D. Professor, Department of Pharmacy Practice and Science, College of Pharmacy, University of Arizona, 4:00-5:00 pm, S538 Phar September 25th 2006: Dr. William Wilber, Noveon, Inc. “Carbopol®, Pemulen® and Noveon® Polymers and Their Use in Drug Delivery Formulations.” 4:00-5:00 pm, S538 Phar October 23rd 2006: Vladimir P. Torchilin, Ph.D., D.Sc.; Distinguished Professor of Pharmaceutical Sciences & Chair, Department of Pharmaceutical Sciences; Director, Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University. 4:00-5:00 pm, S538 Phar November 6th 2006: Michael Mackey, Ph.D.; Associate Professor of Biomedical Engineering, The University of Iowa, 4:00-5:00 pm, S538 Phar November 17th 2006: 2006 Nobel Prize Winner in Medicine - Andrew Z. Fire; Professor of Genetics & Pathology, Stanford University "Cellular Responses to Malicious Information" 11:00 AM Prem Sahai Auditorium (1110A MERF) February 26th 2007: Vicki Grassian, Ph.D.; Professor, Department of Chemistry, The University of Iowa “NNI@UI, XPS and SPM: New Research Opportunities and Capabilities at the University of Iowa”, 4:00-5:00 pm, S538 Phar March 23rd 2007: Victor Lin, Ph.D., Professor, Department of Chemistry, Iowa State University, Rm S307 Pappajohn Business Building, 3.30-4.30pm. March 29th 2007: Surya Mallapragada, Ph.D., Professor, Department of Chemical Engineering and Program Director, Materials Chemistry & Biomolecular Materials, Ames Laboratory, Iowa State University, Shambaugh Auditorium, Main Library, 12.30 pm September 24th 2007: Nita Pandit Ph.D., Professor of Pharmaceutics, Drake University College of Pharmaceutical and Health Sciences, 4:00-5:00 pm, S538 Phar October 1st 2007: Leaf Huang, Ph.D., Fred N. Eshelman Distinguished Professor and Chair of Molecular Pharmaceutics, University of North Carolina School of Pharmacy, 4:00-5:00 pm, S538 Phar October 22nd 2007: Valentino J Stella Ph.D., University Distinguished Professor of Pharmaceutical Chemistry, Kansas University School of Pharmacy, 4:00-5:00 pm, S538 Phar March 10th 2008: Glen Kwon Ph.D., Professor of Pharmaceutical Sciences, University of Wisconsin School of Pharmacy, 4:00-5:00 pm, S538 Phar March 13th 2008: David M. Lynn Ph.D., Assistant Professor, Department of Chemical and Biological Engineering, University of Wisconsin, Madison, 4:00-5:00 pm 3321 Seamans Center May 1st 2008: Paula T. Hammond Ph.D., Bayer Chair Professor of Chemical Engineering, Department of Chemical Engineering, Massachusetts Institute of Technology, 4:00-5:00 pm Seamans Center October 6th 2008: W. Scott Moye-Rowley Ph.D., Professor and Executive Associate Head, The Department of Molecular Physiology and Biophysics, College of Medicine, University of Iowa, 4:00-5:00 pm, S538 Phar October 20th 2008: Diane J. Burgess Ph.D., Professor of Pharmaceutics, Vice President and 2009-2010 President Elect of the Controlled Release Society, University of Connecticut, 4:00-5:00 pm, S538 Phar November 3rd 2008: Alexander V. Kabanov, Ph.D., Dr.Sc. Parke-Davis Professor of Pharmaceutical Sciences, Professor of Genetics, Cell Biology and Anatomy and Professor, Eppley Institute for Research in Cancer Director, Center for Drug Delivery and Nanomedicine College of Pharmacy University of Nebraska Medical Center, 4:00-5:00 pm, S538 Phar February 19th 2009: Samuel A. Wickline, M.D. Professor Internal Medicine Biomedical Engineering Physics Cell Biology and Physiology, Washington University in St Louis, School of Medicine, Targeted Nanoemulsion Theranostics for Cancer and Cardiovascular Disease, 2117 MERF September 8th 2009: Bob Bellantone, Ph.D. Physical Pharmaceutica LLC. 4:00-5:00 pm, S538 Phar September 14th 2009: John Crison, Ph.D. Simulations Plus. 4:00-5:00 pm, S538 Phar December 7th 2009: Frank Szoka, Ph.D. Professor of Biopharmaceutical Sciences and Pharmaceutical Chemistry, University of California, San Francisco. 4:00-5:00 pm, S538 Phar
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